What causes priapism? It’s lack of proteinMarch 14th, 2008 - 12:29 pm ICT by admin
Washington, March 14 (IANS) Scientists have found a new way to treat priapism, or the condition that causes prolonged erection even without a flicker of sexual interest. In a study by researchers at the University of Texas, male mice exhibiting priapism were found to lack the protein ADA, which breaks down the molecule adenosine that causes the disorder.
And ADA therapy helped curb the proliferating adenosine, giving relief to the priapic mice.
Findings of the study have been carried in the latest issue of the Journal of Clinical Investigation.
Considered a medical emergency, Priapism is associated with decreased blood flow to the erectile tissue, which can damage the tissue and cause erectile dysfunction and even impotence.
Poor understanding of its molecular mechanism had stymied efforts at developing an effective treatment.
Yang Xia and colleagues at the University of Texas found that further analysis indicated high levels of adenosine-induced priapism through stimulation of the A2B adenosine receptor in ADA-deficient mice.
The researchers have suggested that approaches to either reduce adenosine levels or block A2B adenosine receptor activation might provide new ways to treat priapism.
- Painful '4-hour erection' may soon be history - Oct 27, 2009
- Relief near for sufferers of constant erections - Mar 14, 2008
- Spider bite can trigger four-hour long erections - Mar 08, 2011
- Staggering 26 pct of Chinese men suffer from erectile dysfunction - Jul 12, 2010
- Spider venom 'could be the new Viagra' - Mar 08, 2011
- Chronic inhalation of polluted air 'can lead to inflammation, heart risk' - Apr 17, 2011
- Giving up smoking gives sex lives a lift, study finds - Aug 23, 2010
- Scientists illuminate cell pathway key to insulin resistance in type 2 diabetes - Feb 25, 2011
- IVF patients advised to drink coffee - Oct 01, 2010
- Male menopause really does exist - Apr 02, 2011
- Researchers say that impotence may double heart attack risk - Mar 17, 2010
- Marijuana use could lead to sexual dysfunction in men - Feb 12, 2011
- Inhaler to cure impotency in 10 minutes - May 19, 2010
- Is Spider venom better than viagra? - Feb 24, 2011
- The secret to longer-lasting sex lies in your arteries - Dec 01, 2010
Tags: ada, adenosine receptor, blood flow, deficient mice, erectile tissue, flicker, impotence, journal of clinical investigation, lack of protein, male mice, medical emergency, molecular mechanism, molecule, new ways, priapism, prolonged erection, receptor activation, sexual interest, university of texas, xia