‘Vampire’ bug shows potential as living antibiotic
November 1st, 2011 - 6:05 pm ICT by IANSWashington, Nov 1 (IANS) A vampire-like bug that preys on specific bacteria, including certain human pathogens, could potentially act as a living antibiotic for a range of infections.
The bacterium, Micavibrio aeruginosavorus, was discovered to inhabit wastewater nearly 30 years ago, but is difficult to culture and examine with traditional microbiology techniques.
However, Martin Wu and graduate student Zhang Wang, biologists at the University of Virginia’s College of Arts & Sciences, have decoded its genome and are learning “how it makes its living”.
The bacterium first seeks out prey, certain other bacteria, and then attaches itself to its victim’s cell wall and essentially sucks out nutrients, the journal BMC Genomics.
Unlike most other bugs, which draw nutrients from their surroundings, M. aeruginosavorus can survive and propagate only by drawing its nutrition from specific prey bacteria.
This kills the prey - making it a potentially powerful agent for destroying pathogens. One bacterium it targets is P aeruginosavorus, which is a chief cause of serious lung infections in cystic fibrosis patients, according to a university statement.
“Pathologists may eventually be able to use this bacterium to fight fire with fire, so to speak, as a bacterium that will aggressively hunt for and attack certain other bacteria that are extremely harmful to humans,” Wu said.
“We used cutting-edge genomic technology in our lab to decode this bacterium’s genome,” he said.
“We are particularly interested in the molecular mechanisms that allow it to hunt for and attack prey. This kind of investigation would have been extremely difficult and expensive to do only a few years ago,” he concluded.
- Gut bugs help battle invading E. coli - May 11, 2012
- Nutrition-starved bugs become resistant to antibiotics - Nov 18, 2011
- Microbes' tricks to kill other bugs may help fight disease - Jul 26, 2011
- Scientists jam bacterial chat to fight virulent infections - Dec 25, 2009
- 'Walking' properties of bacteria discovered - Oct 08, 2010
- Salmonella bugs could prevent food poisoning - Apr 13, 2012
- New discovery may help treatment of multi-drug resistant infections - Jan 06, 2011
- Scientists reveal how superbug turns killer - Oct 17, 2011
- How cholera bug invades the gut - Jan 29, 2012
- Novel drug may benefit cystic fibrosis patients - Dec 18, 2010
- Deadly tool in Salmonella's bag of tricks identified - Feb 04, 2011
- Studying spacebound bacteria may inspire Earthbound remedies - Mar 22, 2011
- Gut bugs have vital bearing on health, immunity - Oct 11, 2011
- New findings on drug tolerance could help cure TB faster - Mar 04, 2011
- Mouth bug could trigger serious illnesses - Feb 22, 2012
Tags: arts sciences, bacteria, bacterium, biologists, bmc, chief cause, cystic fibrosis, cystic fibrosis patients, fire with fire, genome, graduate student, human pathogens, lung infections, microbiology techniques, molecular mechanisms, pathologists, prey, preys, s college, wastewater