New compound can treat resistant TB strainsMarch 15th, 2008 - 3:13 pm ICT by admin
New York, March 15 (IANS) A new compound can prevent active TB in those infected with its latent form, according to medical researchers. The drug could also be useful in treating TB patients by reducing the duration of treatment and in fighting resistant strains.
“With each new case of antibiotic resistance, doctors are losing ground against Mycobacterium tuberculosis and other infectious diseases,” explained the study’s co-author Carl Nathan and Rees Pritchett of Weill Cornell Medical College.
This new approach fights the pathogen in a way that’s different from conventional antibiotics. “We have found compounds that only kill M. tuberculosis when they are not dividing.
“This lack of replication is a characteristic of latent bacteria, which are tough to eradicate with existing antibiotics and ultimately play a huge role in the epidemic’s spread,” they said.
TB kills over 1.6 million people worldwide each year, according to the world health organisation. About a third of the people are believed infected with latent or non-replicating M. tuberculosis.
Currently, it can take six months to eradicate most non-dividing bacteria, and adherence to that long a regimen is difficult for many patients. But if they stop treatment prematurely, drug-resistant bacteria can emerge.
The new findings were published in online issue of Cell Host & Microbe.
- Low-cost pain killer can wipe out resistant TB, say researchers - Sep 13, 2012
- 'Urgent measures needed to control drug resistant TB' - Mar 23, 2012
- Scientists uncover new anti-TB compounds - Sep 17, 2009
- WHO endorses new test for detecting TB in less than 2 hours - Dec 12, 2010
- Gonorrhea cure gets tough as bug grows drug resistant - Nov 08, 2011
- New findings on drug tolerance could help cure TB faster - Mar 04, 2011
- No drug-resistant TB case in India: Expert team - Jan 20, 2012
- New chemical has the potential to eliminate latent TB bacteria - Mar 15, 2008
- 'Time to scale up work on TB control' - Jan 24, 2012
- Central team to probe drug resistant TB cases in Mumbai - Jan 17, 2012
- Honey can help reverse bacterial resistance to antibiotics - Apr 13, 2011
- Standard re-treatment regimen for TB 'failing' in developing world - Mar 16, 2011
- New vaccine strategy tested in mice shows promise against TB - Jan 26, 2011
- New test top diagnoseTB proves effective, convenient - Sep 02, 2010
- Pharma bigwigs join hands for new TB drug - Jun 27, 2012
Tags: adherence, antibiotic resistance, co author, conventional antibiotics, cornell medical college, drug resistant bacteria, infectious diseases, losing ground, medical researchers, new case, pathogen, pritchett, rees, resistant strains, resistant tb, tb patients, tb strains, weill cornell medical, weill cornell medical college, world health organisation