Bio-absorbable stents safe and effective

March 14th, 2008 - 12:10 pm ICT by admin  

London, March 14 (IANS) Bio-absorbable stents are safe and effective in patients with single coronary artery lesions, according to this week’s edition of The Lancet. A fully bio-absorbable coronary stent that scaffolds the vessel wall when needed and disappears once it has remodelled itself has theoretical advantages.

For example, there’s less potential for late stent blockage as there will be no foreign material exposed to the blood if the stent has disappeared into the vessel wall.

Permanent metallic stenting can be susceptible to such blockages and other complications.

Patrick Serruys of Erasmus Medical Center and John Ormiston of Auckland City Hospital studied 30 patients who had ischaemia and a single lesion, suitable for treatment with a single 3×12 mm or 3×18mm stent.

The stent has a backbone and coating of lactic acid helping control the release of everolimus, a drug that prevents scar tissue formation.

The endpoints measured were cardiac death, heart attack, and repeat stenting. Angiographic endpoints were available for 26 patients and ultrasound endpoints for 24 patients.

The researchers found that procedural success was 100 percent and device success was 94 percent (29 out of 31 attempts at implanting the stent). After a one-year follow-up, one of the patients had had a heart attack. No late stent thromboses were recorded.

The authors concluded: “This study shows the feasibility of implantation of the bio-absorbable everolimus-eluting stents. ”

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