3-D MRI pinpoints high-risk bleeding in carotid arterySeptember 16th, 2008 - 4:25 pm ICT by IANS
Toronto, Sep 16 (IANS) Canadian researchers used 3-D magnetic resonance imaging to pinpoint high-risk bleeding within the walls of diseased carotid arteries, a precursor of stroke. Carotid arteries are the ones that supply the head and neck with oxygenated blood. The results suggest the technique may prove to be a useful screening tool for patients at high risk for stroke.
“There’s been a major sea change in our research,” said Alan R. Moody, University of Toronto and co-author of the study. “We now know that the composition of carotid artery plaque is likely to be more predictive of future stroke events than the amount of stenosis (narrowing) in the vessel.”
When major arteries are affected by atherosclerosis, fatty deposits, or plaques, accumulate on the inner lining of the vessel walls. Progression of the disease over time leads to narrowing, restricting blood flow or becoming completely blocked.
Until recently, scientists believed that this narrowing, called stenosis, was responsible for most heart attacks or strokes. But new studies have identified the composition of complicated plaques as being a major cause of vascular events and deaths.
These complicated plaques are characterised by surface ulcerations, blood clots and bleeding into the vessel wall.
Researchers performed 3-D MRI on the carotid arteries of 11 patients, aged 69 to 81. Complicated plaques were then surgically removed from the patients’ diseased arteries and analysed under a microscope.
The research team found strong agreement between the lesions identified by MRI as complicated plaques and the microscopic analysis of the tissue samples.
“With high spatial resolution 3-D MRI, we are able to noninvasively analyse the tissue within the artery wall and identify small bleeds within rupture-prone plaques that may put patients at risk for future stroke,” Moody said.
The study will appear in the October issue of Radiology.
- More strokes, fewer heart attacks with carotid stents: Study - Oct 12, 2010
- New technique to identify potential atherosclerosis risk found - Apr 12, 2011
- Ultrasound technique better alternative to invasive angiography for diagnosing heart disease - Jun 15, 2010
- Breakthrough can re-grow blood vessels in heart - Feb 17, 2012
- Vaccines for heart attacks to be ready within 5 years - Apr 01, 2012
- Presence of iron in artery predicts cardiac risk - Nov 16, 2010
- Spitting debris helps brain's tiny blood vessels survive - Jun 05, 2010
- Chemical in plastic bottles aggravates heart risk - Aug 16, 2012
- Cholesterol-lowering drugs may improve blood flow after stroke - Apr 27, 2011
- MRI may predict stroke onset - Nov 03, 2010
- High fat diet damages arteries earlier than suspected - Apr 04, 2012
- New device removes clots from brain - Aug 27, 2012
- Statin can prevent strokes, besides lowering lipids - Jan 05, 2012
- Low-carb, low-fat and Mediterranean diets 'reverse atherosclerosis in fat people' - Mar 02, 2010
- Slightly high BP raises chances of stroke - Sep 29, 2011
Tags: artery wall, canadian researchers, carotid arteries, d magnetic resonance imaging, diseased arteries, fatty deposits, heart attacks, high spatial resolution, magnetic resonance imaging, major arteries, major sea, microscopic analysis, r moody, restricting blood flow, screening tool, ulcerations, university of toronto, vascular events, vessel wall, vessel walls