Weight loss lowers diabetics’ risk of heart attacksMay 4th, 2012 - 1:15 pm ICT by IANS
Sydney, May 4 (IANS) If obese people with Type 2 diabetes lose even six kilos, it will reduce their arterial stiffness by 20 percent and also the risk of heart attacks, a study reveals.
Diabetes carries a six-fold greater risk of heart disease, which counts for 68 percent of all deaths among people with diabetes, thanks to hardening of the arteries (atherosclerosis).
Associate professors Katherene Samaras from Garvan Institute of Medical Research and Christopher Hayward from St. Vincent’s Hospital, have shown that arterial stiffness is directly tied with inflammation and immune response to infection or illness, the journal Diabetes and Vascular Disease Research reported.
The study was based on a group of obese people with Type 2 diabetes or pre-diabetes. All participants underwent a calorie-restricted diet for 24 weeks, with gastric banding surgery after 12 weeks, according to a statement Garvan and St. Vincent Hospital.
“We found that the degree of inflammation in fat tissue specifically predicted how much arteries relaxed during a weight loss programme, meaning that people with higher levels of inflammation had arteries that did not relax as much,” said Samaras.
“Obesity, Type 2 diabetes and atherosclerosis are all associated with an inflammatory state, involving activation of immune cells in the circulation and in fat tissue, as well as an increase of circulating pro-inflammatory molecules,” Samaras added.
“Weight loss reduces immune cell activation and inflammation, which in turn is related to the extent that arteries can relax. To our knowledge, this is the first study to examine the relationships between weight loss-induced improvements in arterial stiffness and the immune response,” concluded Samaras.
- Losing just 6kgs 'enough for big health gain' - Apr 20, 2010
- Weight loss helps boost low testosterone levels - Jun 26, 2012
- Low-calorie diet tied to bowel disease deaths - Mar 21, 2012
- What babies eat determines risk of obesity - Aug 31, 2012
- Link between high-fat diets, type 2 diabetes clarified - Apr 12, 2011
- Targeting fatty acids in immune cells may cut atherosclerosis risk - Jul 24, 2010
- Human enzyme holds promise of weight loss - Nov 15, 2011
- Apple compound may help burn fat, reduce obesity - Jun 21, 2012
- Gene network behind hardening arteries identified - Sep 19, 2010
- High fat diet damages arteries earlier than suspected - Apr 04, 2012
- Tangerines help prevent obesity, protect against heart disease - Apr 07, 2011
- Insulin reduces obesity-related inflammation - May 11, 2010
- Why some people are apple-shaped and others pear-shaped - Mar 10, 2011
- BP drug lowers weight in spite of high fat diet - Apr 13, 2012
- New study reinforces belly fat, high-fat meals and heart disease link - Feb 18, 2011
Tags: arterial stiffness, arteries, associate professors, calorie restricted diet, garvan institute of medical research, heart attacks, heart disease, immune cell, immune cells, immune response, inflammation, inflammatory state, journal diabetes, pre diabetes, risk of heart disease, s hospital, samaras, st vincent hospital, type 2 diabetes, vascular disease