Statins stave off depression in heart patientsFebruary 26th, 2012 - 7:18 pm ICT by IANS
Washington, Feb 26 (IANS) Heart patients who take cholesterol-lowering statins are less likely to develop depression than those who did not.
Mary Whooley, professor of medicine at the University of California, San Francisco and her research team evaluated 965 heart patients for depression.
They found that the patients who were on statins were significantly less likely to be clinically depressed than those who were not, the Journal of Clinical Psychiatry reports.
They then followed the 776 patients who were not depressed - 520 who were using statins and 256 who were not - for an additional six years, according to a California statement.
Of those taking statins, 18.5 percent developed depression, compared with 28 percent of those not on the drugs. Put another way, the patients who took statins were 38 percent less likely to develop depression than patients who did not.
As the study went on, said Whooley, the difference between the two groups became more pronounced, with the patients on statins becoming less likely to develop depression and the patients not on statins becoming more likely to become depressed over time.
“This would suggest that statins may have some kind of long-term protective effect against depression, perhaps by helping to prevent atherosclerosis in the brain, which can contribute to depressive symptoms,” Whooley said.
She also noted that statins have positive effects on the endothelium - the inner lining of the blood vessels - keeping blood vessels less rigid and therefore better able to adapt to the body’s changing needs. “The exact mechanism is not known, however, and requires further study,” she said.
- Cholesterol busting drugs might be bad for you - Dec 21, 2010
- Statins can cut prostate cancer risk - Oct 02, 2011
- Cholesterol-lowering drug could protect kidneys after surgery - Apr 12, 2011
- Statins reduce pneumonia death rates: Study - Apr 05, 2011
- Cholesterol-lowering drugs may improve blood flow after stroke - Apr 27, 2011
- 'Statins prevent cancer in heart transplant patients' - May 20, 2012
- Biomarker can nip hardening of arteries in the bud - Jan 22, 2012
- Statins may help prevent blood clots in heart patients - Nov 04, 2009
- 'Good' cholesterol drug may help diabetics - Jul 19, 2011
- Statins 'may prevent re-growth of prostate cancer' - Jun 28, 2010
- Low iron levels tied to blood clot risk - Dec 15, 2011
- Why statins work for some people, but not for all - Apr 22, 2010
- Cholesterol-lowering statins 'kill bacteria' - Nov 18, 2010
- Anti cholesterol drug causes depression: Indian scientists - Jun 23, 2010
- Treating high BP, cholesterol, diabetes may delay Alzheimer's - Apr 14, 2011
Tags: blood vessels, brain, california san francisco, cholesterol, depression, depressive symptoms, drugs, endothelium, exact mechanism, further study, heart patients, journal of clinical psychiatry, mary whooley, medicine, six years, statins, university of california, university of california san francisco