Plastic bottle compound harms several generationJune 17th, 2012 - 2:46 pm ICT by IANS
Washington, June 17 (IANS) Exposure to low doses of Bisphenol A (BPA), a toxic man-made chemical, during gestation has immediate and long-lasting trans-generational effects on the brain and social behaviour, says a study.
BPA is present in a variety of products including plastic water bottles, food containers, receipt paper and dental sealants and is now widely detected in human urine and blood.
Public health concerns have been fuelled by findings that BPA exposure can influence brain development. In mice, prenatal exposure to BPA is linked with increased anxiety, aggression and cognitive impairments, the journal Endocrinology reported.
“We have demonstrated for the first time to our knowledge that BPA has trans-generational actions on social behaviour and neural expression,” said Emilie Rissman, of the University of Virginia School of Medicine who led the study.
“Since exposure to BPA changes social interactions in mice at a dose within the reported human levels, it is possible that this compound has trans-generational actions on human behaviour,” said Rissman, said a university statement.
“If we banned BPA tomorrow, pulled all products with BPA in them, and cleaned up all landfills tomorrow it is possible, if the mice data generalize to humans, that we will still have effects of this compound for many generations,” said Rissman.
In this study, female mice received chow with or without BPA before mating and throughout gestation. Plasma levels of BPA in supplemented female mice were in a range similar to those measured in humans.
“BPA is a ubiquitous chemical, it is in the air, water, our food, and our bodies,” said Rissman. “It is a man-made chemical, and is not naturally occurring in any plant or animal.
“The fact that it can change gene expression in mice, and that these changes are
heritable, is cause for us to be concerned about what this may mean for human health,” added Rissman
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- Foetal exposure to chemical BPA causes problems in girls - Oct 24, 2011
- Exposure to low doses of BPA alters mice ovaries - Aug 26, 2010
- Early-life exposure to BPA may harm testis function in adulthood - Jun 22, 2010
- Human exposure to plastics chemical much higher than previously thought - Sep 21, 2010
- Exposure to plastics chemical linked to reduced semen quality - Oct 28, 2010
- Exposure to toxic chemical higher than suspected - Jun 06, 2011
- BPA exposure may lead fertility problems in female offspring - Dec 02, 2010
- High plastic chemical levels in urine ruins males' sex drive - May 28, 2010
- Prenatal exposure to chemical in plastic linked to wheezing in kids - May 02, 2011
- Packaging chemical could cheat men of sex appeal - Jun 29, 2011
- Potency wrecking compound linked to heart disease - Feb 24, 2012
- Exposure to Bisphenol A may cause male impotence - Nov 11, 2009
- Mum's exposure to some plastic may increase kid's asthma risk - Feb 04, 2010
- Food packaging harbours harmful toxins - Mar 31, 2011
Tags: bpa, brain development, dental sealants, female mice, food containers, gene expression, human behaviour, human urine, journal endocrinology, many generations, plasma levels, plastic water bottles, prenatal exposure, public health concerns, receipt paper, rissman, social behaviour, social interactions, toxic man, virginia school