Lens-less microscope produces sharp 3-D imagesApril 25th, 2011 - 3:08 pm ICT by IANS
Washington, April 25 (IANS) A lens-less microscope small enough to sit on the palm of your hand has enough punch to create 3D images of miniscule samples.
The technique demonstrates a lens-free optical tomographic imaging on a chip for the first time, capable of producing high-resolution 3-D images of large volumes of microscopic objects.
“This research clearly shows the potential of lens-free computational microscopy,” said Aydogan Ozcan, senior study author and associate professor of electrical engineering at University of California-Los Angeles School of Engineering and Applied Science.
“Wonderful progress has been made in recent years to miniaturize life-sciences tools with microfluidic and lab-on-a-chip technologies, but until now optical microscopy has not kept pace with the miniaturisation trend,” the journal proceedings of the National Academy of Sciences reports.
An optical imaging system small enough to fit onto an opto-electronic chip provides a variety of benefits, according to a California statement.
Because of the automation involved in on-chip systems, scientific work could be sped up significantly, which might have a great impact in the fields of cell and developmental biology.
Besides, the small size not only has great potential for miniaturising systems but also leads to cost savings on equipment.
The optical microscope, invented more than 400 years ago, has tended to grow larger and more complex as it has been modified to view ever-smaller objects with better resolution.
The system takes advantage of the fact that organic structures, such as cells, are partially transparent. So by shining a light on a sample of cells, the shadows created reveal not only the cells’ outlines but details about their sub-cellular structures as well.
- Cutting edge microscopy tracks cellular traffic - Sep 18, 2012
- World's smallest, lightest telemedicine microscope invented - Apr 23, 2010
- World's tiniest, lightest microscope designed - Apr 23, 2010
- Engineers invent lens for 3D microscope - Mar 22, 2011
- Now, a quick and affordable microfluidic HIV test - Jul 17, 2010
- Better healthcare through your cell phone posssible - Sep 15, 2008
- GE Healthcare's new imaging system captures live cells - Nov 01, 2011
- Lens-free imaging to help cell phones monitor HIV, malaria from afar - Dec 23, 2008
- Cell phones can now monitor HIV and malaria patients'' conditions - Dec 23, 2008
- Scientists image working brain cell in real time - Feb 07, 2012
- Single lens produces 3D microscopic images - Mar 22, 2011
- New laser-based tool 'detects signs of skin cancer' - Feb 24, 2011
- New liquid lens for high-resolution imaging below the skin - Feb 21, 2011
- New study shows promise against typhoid-causing bacteria - Mar 05, 2011
- World's most powerful microscope could 'solve the cause of viruses' - Mar 02, 2011
Tags: 3d images, applied science, cellular structures, chip systems, chip technologies, developmental biology, electronic chip, imaging system, journal proceedings, microfluidic, national academy of sciences, optical imaging, optical microscope, optical microscopy, organic structures, palm of your hand, proceedings of the national academy, proceedings of the national academy of sciences, tomographic imaging, university of california los angeles