drug targets

Scientists pinpoint brain receptor linked with rage


June 20th, 2012 - 3:57 pm ICT by IANS
Washington, June 20 (IANS) Scientists have identified a brain receptor, an enzyme monoamine oxidase A, whose malfunctioning can trigger sudden violence, explosive outbursts and hostile overraction to stress in mice. ... Read more...

Posted in World |

Robotic arm to reveal inner working of brain cells


May 7th, 2012 - 2:01 pm ICT by IANS
Washington, May 7 (IANS) Gaining access to the inner workings of a brain cell (neuron) in real time offers a wealth of useful information. However, it is such a painstaking ... Read more...

Posted in World |

Estrogen found to protect against gastric cancer


July 18th, 2011 - 6:34 pm ICT by IANS
Washington, July 18 (IANS) Researchers have found that estrogen protects women from the gastric inflammation that can lead to cancer. They are working on treatment that mimics estrogen's cancer-suppressing effects. ... Read more...

Posted in World |

Potential therapeutic target for Staph infections discovered


April 13th, 2011 - 5:39 pm ICT by ANI
Washington, April 13 (ANI): Scientists have discovered two genes that encode copper and sulfur-binding repressors in the Staphylococcus aureus, which they say could provide two new potential avenues for controlling the increasingly ... Read more...

Posted in Health Science |

‘Dual switch’ that regulates fat formation may harbour obesity cure


April 9th, 2011 - 12:56 pm ICT by ANI
Washington, April 09 (ANI): A new study has identified a key regulator of fat cell development that may provide a target for obesity and diabetes drugs.The scientists at the Scripps Research Institute ... Read more...

Posted in Health Science |

Molecules that help propel cancer metastasis identified


April 8th, 2011 - 2:28 pm ICT by ANI
Washington, April 08 (ANI): Researchers at Albert Einstein College of Medicine of Yeshiva University have identified two molecules that enable cancer to spread inside the body.The findings could eventually lead to ... Read more...

Posted in Health Science |

Genetic change helps lung tumors spread to other parts of the body


April 7th, 2011 - 6:14 pm ICT by ANI
London, April 7 (ANI): Scientists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body.The findings offers new insight into how lung cancers ... Read more...

Posted in Health Science |

New study could lead to potential drug targets for schizophrenia, Parkinson’s


March 12th, 2011 - 4:32 pm ICT by ANI
Washington, Mar 12 (ANI): A new study from the Scripps Research Institute and University of Pennsylvania could pave the way for potential drug targets for diseases ranging from schizophrenia to Parkinson's disease.By ... Read more...

Posted in Health Science |

Irreversible inhibition of a protease central to hepatitis C infection: Study


November 29th, 2010 - 3:02 pm ICT by ANI
London, Nov 29 (ANI): A new study has demonstrated that irreversible covalent inhibition can increase selectivity, potency and duration of action, broadens applications for targeted covalent drugs to the protease gene family.Avila ... Read more...

Posted in Health Science |

Plants, animals use similar mechanism when fending off diseases


November 19th, 2010 - 6:20 pm ICT by ANI
Washington, Nov 19 (ANI): Through the ages, plants and animals have developed strikingly similar mechanisms for detecting microbial invasions and resisting diseases, says a new study.This revelation is a result 15 years ... Read more...

Posted in Health Science |

Key enzyme that controls growth of breast cancer cells identified


November 19th, 2010 - 6:08 pm ICT by ANI
Washington, Nov 19 (ANI): A new study has found that blocking the action of an enzyme called GnT-V could delay the onset and spread of tumours with human breast cancer.When the GnT-V ... Read more...

Posted in Health Science |

Drug targets defective protein that causes cystic fibrosis


November 18th, 2010 - 4:43 pm ICT by ANI
London, Nov 18 (ANI): A new small study has shown that an investigational drug targeting a defective protein that causes cystic fibrosis (CF) can improve lung function.The investigational drug, VX-770, appeared to ... Read more...

Posted in Health Science |

Drug used to treat asthma ‘prevents spread of breast cancer’


November 4th, 2010 - 1:54 pm ICT by ANI
Washington, Nov 04 (ANI): A new study has shown that a drug commonly used in Japan and Korea to treat asthma can stop the spread of breast cancer cells traditionally resistant to ... Read more...

Posted in Health Science |

India-origin scientist’s findings may hold key to novel malaria vaccines


October 22nd, 2010 - 1:48 pm ICT by ANI
Washington, Oct 22 (ANI): Out of the 72 molecular switches that control the three key stages in the life cycle of the malaria parasite, over a third of these switches can be ... Read more...

Posted in Health Science |

Four new psoriasis ‘hotspots’ identified


October 19th, 2010 - 4:57 pm ICT by ANI
Washington, Oct 19 (ANI): Scientists have discovered four new DNA "hotspots" that may one day help guide new treatments for psoriasis, one of the most common autoimmune diseases in the country.The ... Read more...

Posted in Health Science |

Molecular on-off switches for cancer and autoimmunity defined


October 1st, 2010 - 2:40 pm ICT by ANI
Washington, Oct 1 (ANI): Scientists from the Institute for Advanced Studies in New Jersey are examining how oncogenes and tumour suppressor genes handle cellular stress, and said that each of these opposing ... Read more...

Posted in Health Science |

New investigational drug targets pancreatic cancer cells


September 16th, 2010 - 4:55 pm ICT by ANI
Washington, Sep 16 (ANI): A patient at the Virginia G. Piper Cancer Center at Scottsdale Healthcare has been administered a new investigational drug designed to penetrate and attack pancreatic cancer cells.ASG-5ME is ... Read more...

Posted in Health Science |

Muscular dystrophy gene mystery cracked


August 20th, 2010 - 2:52 pm ICT by ANI
Washington, Aug 20 (ANI): Scientists have made a critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral dystrophy, or FSHD.They have identified a DNA ... Read more...

Posted in Health Science |

New discovery could pave way for anti-aging drugs


August 19th, 2010 - 3:16 pm ICT by ANI
Washington, Aug 19 (ANI): A team of University of Michigan scientists has found that suppressing a certain gene in roundworms extended their lifespan.The U-M results could pave the way for discovery of ... Read more...

Posted in Health Science |

Soon, an ‘intelligent diet’ to feel full and yet lose weight


August 13th, 2010 - 1:50 pm ICT by ANI
London, Aug 13 (ANI): Researchers in Aberdeen are working on an 'intelligent diet', which they believe will allow people to enjoy eating and feeling full, but still lose weight.Professor Julian Mercer, the ... Read more...

Posted in Health Science |

How malaria-causing parasites survive inside human blood cells


August 5th, 2010 - 4:18 pm ICT by ANI
Washington, Aug 5 (ANI): Scientists have discovered a new metabolic pathway used by malaria-causing parasites that apparently helps them survive inside human blood cells.The finding, by researchers supported by the National ... Read more...

Posted in Health Science |

95 genetic variants linked to heart disease identified


August 5th, 2010 - 12:10 pm ICT by ANI
London, Aug 5 (ANI): An international team of researchers co-led by the University of Michigan School of Public Health has found 95 regions of the human genome where genetic variants are associated ... Read more...

Posted in Health Science |

New fluorescent biosensor to aid drug development


July 30th, 2010 - 4:09 pm ICT by ANI
Washington, July 30 (ANI): Carnegie Mellon researchers have come up with a new fluorescent biosensor that could aid in the development of an important class of drugs that target a crucial class ... Read more...

Posted in Health Science |

Genomic analysis of prostate cancer unveiled


June 26th, 2010 - 4:11 pm ICT by ANI
Washington, June 26 (ANI): Scientists have assembled the most comprehensive genomic analysis of prostate cancer to date.The hope is that the database will result in new drug targets and the development ... Read more...

Posted in Health Science |

Study sheds light on metabolic vulnerability in TB and potential drug target


May 11th, 2010 - 1:28 pm ICT by ANI
Washington, May 11 (ANI): Scientists at Weill Cornell Medical College have shed light on a previously unrecognised aspect of fatty acid metabolism in tuberculosis (TB) that could potentially lead to new targets ... Read more...

Posted in Health Science |

Scientists unravel link between stress, anxiety, depression


April 12th, 2010 - 3:04 pm ICT by IANS
Toronto, April 12 (IANS) Scientists have unravelled the link between stress, anxiety and depression. By identifying the connecting mechanism in the brain, the research led by Stephen Ferguson of the Robarts Research ... Read more...

Posted in Health |

Biological link between stress, anxiety and depression discovered


April 12th, 2010 - 12:08 pm ICT by ANI
London, April 12 (ANI): A team of researchers at The University of Western Ontario has identified the biological link between stress, anxiety and depression.By identifying the connecting mechanism in the brain, ... Read more...

Posted in Health Science |

New one-off treatment may help cure rheumatoid arthritis


April 12th, 2010 - 2:33 am ICT by IANS
London, April 12 (IANS) British scientists claim to have developed one-off treatment which could potentially help cure rheumatoid arthritis. The crippling joint disease is triggered by attacks from the body's own ... Read more...

Posted in Health |

2-pronged approach required for inflammation prevention after heart attack, stroke


March 1st, 2010 - 2:16 pm ICT by ANI
Washington, Mar 1 (ANI): Albany Medical College researchers have come up with a new research which they claim will help refocus the search for new drug targets aimed at preventing or reversing ... Read more...

Posted in Health Science |

New risk factor for second-most-common cause of early dementia onset found


February 16th, 2010 - 5:05 pm ICT by ANI
London, Feb 16 (ANI): American researchers have found a new risk factor for second-most-common form of early-onset dementia after Alzheimer's.Researchers from the University of Pennsylvania School of Medicine and the Children's Hospital ... Read more...

Posted in Health Science |

Drug shows promise against river blindness


February 10th, 2010 - 3:36 pm ICT by ANI
Washington, Feb 10 (ANI): Closantel, an old drug used to treat sheep and cattle infected with liver fluke, may prove effective in fighting river blindness in humans, a major cause of infection-related ... Read more...

Posted in Health Science |

New drug targets for malaria cure


January 12th, 2010 - 12:30 pm ICT by ANI
Washington, Jan 12 (ANI): An international team of scientists has made a novel discovery that would help in the development of new drugs to help cure malaria.They have identified normal function of ... Read more...

Posted in Health Science |

Single atom controls how bacteria walk


January 5th, 2010 - 5:09 pm ICT by ANI
Washington, Jan 5 (ANI): Researchers at the University of North Carolina at Chapel Hill have found that a single atom - a calcium, can control how bacteria walk.Bacteria can swim, propelling ... Read more...

Posted in Health Science |

Why can’t chimps speak like their human cousins?


November 12th, 2009 - 5:03 pm ICT by IANS
Washington, Nov 12 (IANS) If humans are genetically related to chimps, why did our brains develop the innate ability for language and speech while theirs did not? Scientists suspect that part of the ... Read more...

Posted in Sci-Tech |

Why chimps can’t chat


November 12th, 2009 - 12:33 pm ICT by ANI
London, Nov 12 (ANI): A mutation in a gene might help explain why chimps, our nearest relative, don't talk, claim scientists.It is known that when mutated, FOXP2 can disrupt speech and language ... Read more...

Posted in Health Science |

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