drug target

Scientists identify four anti-cancer compounds


November 30th, 2011 - 2:31 pm ICT by IANS
Sydney, Nov 30 (IANS) Four new anti-cancer compounds have shown promise in inhibiting the growth of tumours, according to a new approach.Jason Smith, doing his M.Phil. in biomolecular sciences from ... Read more...

Posted in Health |

Enzyme crucial to DNA replication may be potent anti-cancer drug target


April 15th, 2011 - 6:42 pm ICT by ANI
Washington, April 15 (ANI): Scientists have found that an enzyme essential for DNA replication and repair in humans works in a way that might be exploited as an anti-cancer therapy.Researchers at The ... Read more...

Posted in Health Science |

Zebrafish offers skin cancer clues


April 6th, 2011 - 2:53 pm ICT by ANI
London, Apr 6 (ANI): Zebrafish has offered new hope to people with melanoma, an aggressive form of skin cancer.Researchers identified SETDB1 as a new gene that promotes the growth of melanoma and ... Read more...

Posted in Health Science |

New drug target for inflammatory bowel disease found


April 1st, 2011 - 2:48 pm ICT by ANI
Washington, April 1 (ANI): Scientists have identified IL-23, a cytokine used by the immune system to ward off disease, as a major contributor to the inflammatory bowel disease (IBD).The new discovery raises ... Read more...

Posted in Health Science |

How mutations in a gene cause Parkinson’s disease


March 26th, 2011 - 2:30 pm ICT by ANI
Washington, March 26 (ANI): Scientists have found a way that mutations in a gene called LRRK2 may cause the most common inherited form of Parkinson's disease.The study, conducted by researchers at Mount ... Read more...

Posted in Health Science |

Finding of long-sought drug target structure may accelerate drug discovery


March 16th, 2011 - 4:08 pm ICT by ANI
Washington, Mar 16 (ANI): Researchers from the National Institutes of Health, collaborating with labs at The Scripps Research Institute and the University of California, San Diego, have solved the three-dimensional structure of ... Read more...

Posted in Health Science |

New genetic signatures of breast cancer drug resistance identified


January 11th, 2011 - 6:03 pm ICT by ANI
Washington, Jan 11 (ANI): Researchers have identified more than 30 breast cancer gene targets-including several novel genes-that are involved in drug resistance to a leading chemotherapy treatment.The study conducted by Josh LaBaer's ... Read more...

Posted in Health Science |

New discovery may lead to advances in treating anxiety disorders


January 8th, 2011 - 2:05 pm ICT by ANI
Washington, Jan 08 (ANI): UCLA life scientists have discovered what may be a completely unexplored drug target for the treatment of anxiety disorders.Normally, when people or animals experience a frightening event, ... Read more...

Posted in Health Science |

Oz scientists make breast cancer breakthrough with protein discovery


October 2nd, 2010 - 4:14 pm ICT by ANI
New Delhi, Oct 2 (ANI): Making a huge breakthrough in potential breast cancer treatment, Australia's Brisbane-based researchers have found that the concentration of a protein that moves calcium into a specific area ... Read more...

Posted in Health Science |

Scientists discover new drug target for immune diseases


August 4th, 2010 - 4:33 pm ICT by ANI
London, August 04 (ANI): Scientists have found a new mechanism that explains how certain immune cells are activated to create protective antibodies against infections or pathological antibodies such as those present in ... Read more...

Posted in Health Science |

How memory is disrupted in people with disease linked to learning disabilities


July 17th, 2010 - 3:48 pm ICT by ANI
Washington, July 17 (ANI): By uncovering how a genetic condition, called neurofibromatosis type 1, or NF1, disrupts working memory, researchers at UCLA have suggested a potential drug target for correcting learning disabilities ... Read more...

Posted in Health Science |

Protein that thwarts tumor invasion uncovered


June 6th, 2010 - 1:11 pm ICT by ANI
Washington, June 6 (ANI): Cancer cells lacking a key protein are more invasive and more likely to metastasize, providing a possible drug target to combat certain tumor types, scientists at UT Southwestern ... Read more...

Posted in Health Science |

Study sheds light on metabolic vulnerability in TB and potential drug target


May 11th, 2010 - 1:28 pm ICT by ANI
Washington, May 11 (ANI): Scientists at Weill Cornell Medical College have shed light on a previously unrecognised aspect of fatty acid metabolism in tuberculosis (TB) that could potentially lead to new targets ... Read more...

Posted in Health Science |

Study promises defence against diarrhoea


April 26th, 2010 - 6:51 pm ICT by ANI
Washington, April 26 (ANI): The findings of a new American research could soon provide defence against infections caused by waterborne microscopic pathogen cryptosporidium.Found in swimming pools, water parks, and drinking water supplies, ... Read more...

Posted in Health Science |

Breast stem cells’ hormone sensitivity presents new drug target


April 12th, 2010 - 5:11 pm ICT by ANI
London, Apr 12 (ANI): Breast stem cells are exquisitely sensitive to the female hormones oestrogen and progesterone, according to researchers at the Walter and Eliza Hall Institute.The discovery opens the way for ... Read more...

Posted in Health Science |

Why Huntington’s disease symptoms take so long to appear


February 24th, 2010 - 6:03 pm ICT by ANI
Washington, Feb 24 (ANI): A new Canadian study has discovered a protective pathway in the brain that could help explain why Huntington's disease (HS) symptoms take so long to appear.HD is hereditary ... Read more...

Posted in Health Science |

Why Tamoxifen fails to work on some breast cancer patients


February 24th, 2010 - 2:26 pm ICT by ANI
London, Feb 24 (ANI): British scientists have revealed that they have found why some women suffering from breast cancer do not respond to treatment by the drug Tamoxifen.According to them, the drug ... Read more...

Posted in Health Science |

Gene variant linked to a form of irregular heartbeat identified


February 22nd, 2010 - 5:06 pm ICT by ANI
London, Feb 22 (ANI): Researchers have identified a common gene variant associated with a form of the irregular heartbeat called atrial fibrillation.It is a condition in which the upper chambers of the ... Read more...

Posted in Health Science |

New weapon to fight malaria, disease-causing bacteria developed


February 16th, 2010 - 1:32 pm ICT by ANI
Washington, Feb 16 (ANI): University of Illinois researchers have discovered an unusual chemical reaction mechanism that allows malaria parasites and many disease-causing bacteria to survive.The research team even knows how to ... Read more...

Posted in Health Science |

New drug target may help reduce muscle damage caused by heart attacks


January 11th, 2010 - 12:58 pm ICT by ANI
London, Jan 11 (ANI): An international team of researchers have discovered a potential therapeutic target that could help reduce muscle damage caused by heart attacks.They have explained how a "chemical chaperone" does ... Read more...

Posted in Health Science |

New drug target may help treat chronic rhinosinusitis with polyps


November 23rd, 2009 - 5:22 pm ICT by ANI
Washington, Nov 23 (ANI): Johns Hopkins researchers have identified a protein that is responsible for causing chronic rhinosinusitis with polyps.Chronic sinusitis, a constant irritation and swelling of the nasal passages, is a ... Read more...

Posted in Health Science |

Two-gene interaction could offer more targeted cancer treatment


November 11th, 2009 - 4:32 pm ICT by ANI
Washington, Nov 11 (ANI): Queen's University researchers have found a link between two genes involved in cancer formation in humans.The groundbreaking discovery could offer a foundation for how tumour-forming genes interact, ... Read more...

Posted in Health Science |

Key protein behind pulmonary arterial hypertension identified


October 26th, 2009 - 12:49 pm ICT by ANI
London, Oct 26 (ANI): In a groundbreaking discovery, researchers at the University of California, San Diego, have identified a key protein that promotes the development of pulmonary arterial hypertension in humans and ... Read more...

Posted in Health Science |

Identification of potential drug target gives new hope for Alzheimer’s patients


July 2nd, 2009 - 11:30 am ICT by ANI
London, July 2 (ANI): A collaborative study conducted by researchers from UC Santa Barbara and several other institutions has provided laboratory that a cluster of peptides may be the toxic agent in ... Read more...

Posted in Health Science |

Scientists uncover malfunctioning gene behind gout


June 19th, 2009 - 5:10 pm ICT by ANI
Washington, June 19 (ANI): Johns Hopkins scientists have found that a malfunctioning gene they helped uncover last year can lead to high concentrations of blood urate that forms crystals in joint tissue ... Read more...

Posted in Health Science |

Protein involved in leukemia plays mixed role in breast cancer development


June 14th, 2009 - 11:25 am ICT by ANI
Washington, June 14 (ANI): A protein involved in the growth of some forms of leukemia has now been found to play a mixed role in breast cancer development, say researchers.Experts from the ... Read more...

Posted in Health Science |

New therapeutic target for pancreatic cancer found


April 19th, 2009 - 4:31 pm ICT by ANI
Washington, Apr 19 (ANI): A research team led by Indian origin scientist has identified a potential target for pancreatic cancer, one of the most fatal cancers.Akhilesh Pandey, a Johns Hopkins University pathologist ... Read more...

Posted in Health Science |

Coming soon, a sureshot way to treat constipation


April 9th, 2009 - 12:23 pm ICT by ANI
Washington, April 9 (ANI): Suffering from constipation? Well, help is on the way - a team of researchers has identified a potential drug target to make it a lot easier to go ... Read more...

Posted in Health Science |

Space experiment sheds new light on bone loss


March 31st, 2009 - 4:11 pm ICT by ANI
Washington, March 31 (ANI): A space experiment conducted by Italian scientists has for the first time shown that a lack of resistance, that is gravity, activates bone-destroying cells.An article on the study ... Read more...

Posted in Health Science |

Scientists decode TB enzyme, open way to new drugs


March 28th, 2009 - 4:55 pm ICT by IANS
Washington, March 28 (IANS) Scientists have decoded the unique structure and mechanism of a tuberculosis enzyme, paving the way for development of new drugs to combat active and latent tuberculosis infections. Barbara Gerratana, ... Read more...

Posted in Health |

TB enzyme’s discovery brings new drug therapies closer to reality


March 28th, 2009 - 10:55 am ICT by ANI
Washington, March 28 (ANI): University of Maryland scientists have reached a step closer to developing new drug therapies to combat active and asymptomatic (latent) tuberculosis infections by characterizing the unique structure and ... Read more...

Posted in Health Science |

Potential new drug target to stop Alzheimer’’s progression identified


March 20th, 2009 - 1:02 pm ICT by ANI
Washington, Mar 20 (ANI): Scientists have moved a step closer to developing a drug that could actually stop the progress of Alzheimer''s disease.They have identified a molecule that can form the ... Read more...

Posted in Health Science |

New drug target to combat Alzheimer’’s disease identified


February 13th, 2009 - 12:40 pm ICT by ANI
Washington, Feb 13 (ANI): Scientists at the Flanders Institute for Biotechnology (VIB) claim that they have discovered a potential therapeutic target for Alzheimers disease.The team led by Amantha Thathiah, in collaboration ... Read more...

Posted in Health Science |

Novel drug target for severe allergic reactions identified


January 30th, 2009 - 5:38 pm ICT by ANI
Washington, Jan 30 (ANI): An international team of researchers has identified a novel target that may lead to the development of new class of allergy drugs.The researchers have come across a ... Read more...

Posted in Health Science |

Biochemical switch needed for nerve cells to respond to DNA damage identified


January 19th, 2009 - 2:07 pm ICT by ANI
London, January 19 (ANI): Scientists at Emory University School of Medicine have announced the identification of a biochemical switch, which is required for nerve cells to respond to DNA damage. The researchers ... Read more...

Posted in Health Science |

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