Secondhand smoke at home affects toddlers heart health the most

March 14th, 2008 - 11:26 am ICT by admin  

Washington, Mar 14 (ANI): If you want your baby to grow up healthy, then you need to stop smoking at home, warns a new study which found that secondhand smoke at home appears to induce markers for heart disease as early as the toddler years.

The study was carried out by researchers at Nationwide Childrens Hospital and Research Institute in Columbus, Ohio, and is the first that shows that a young kids response to smoke may not only affect his or her respiratory system, but also the cardiovascular system.

As a part of the study, boffins led by Dr. Judith Groner analysed 128 children between they age of 2 to 5 years old and adolescents between the age of 9 to 14.

They found that kids from the younger age group absorb six times more nicotine than their older counterparts from the same levels of parental smoking.

This exposure is what results in a dramatic increase of marker of inflammation soluble intracellular adhesion molecules (ICAM) and vascular injury signalling damage to the endothelium, the inner lining of the vessel walls that plays a key role in promoting cardiovascular health by maintaining the tone and circulation of the arteries.

ICAM is a specific marker of endothelial cell stress, which contributes to artery clogging and atherosclerosis, raising the risk of heart disease.

Toddlers in the homes of smokers not only had higher levels of nicotine, but also had higher levels of markers for cardiovascular disease in the blood, said John Bauer, Ph.D., senior author of the study and director of the Center for Cardiovascular Medicine at Nationwide Childrens Hospital and Research Institute in Columbus, Ohio.

The dose of smoke is greater in toddlers than adolescents who are able to move in and out of the home. Toddlers are like a fish in a fishbowl. They are exposed at a higher dose. And it appears that toddlers also are more susceptible to the cardiovascular effects of smoke.

Dr Groner added: When we analyzed our data by looking at the relationships between the number of smokers in the home and the EPC levels, we found that in toddlers, there was an inverse relationship between secondhand smoke exposure and EPC prevalence. In other words, the more smokers the toddler was exposed to, the fewer EPC cells were circulating in his bloodstream. This relationship was not present among the adolescents.

The combustion of the cigarettes appears to be causing endothelial damage which is reflected in the increase in soluble ICAM in exposed children. Toddlers who are in the vicinity of smokers in the home have a higher dose of tobacco chemicals. They live at home and cant escape. Young children also breathe faster, taking more smoke into their respiratory system.

Dr Groner added that more study was needed in this field.

The results are intriguing, but further study is needed. Were not sure what happens to kids if they stay in a smoking environment or if they have multiple risk factors such as being overweight or having high blood pressure. Until then, parents and others should not smoke in homes with children, and should be especially attentive to this issue around toddlers, she said.

The study was presented at the American Heart Associations 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention. (ANI)

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