Synthetic hormone treatment reduces swollen livers

August 18th, 2009 - 6:07 pm ICT by IANS  

London, Aug 18 (IANS) A six-month treatment with a synthetic gastro-intestinal hormone, Lanreotide, significantly decreased swollen cystic livers, compared to a ‘wait and see’ policy, says a new research.
At least five percent of the population have one or two cysts in the liver. Cysts are fluid-filled cavities. There are also many patients who have numerous cysts - a polycystic liver.

These cysts cause the liver to grow to four to six times its normal size. Until recently, surgery was the only possible treatment for these patients, but surgery leads to many complications, and the outcome is not always successful.

Ultimately, these patients need a liver transplantation, but in view of the limited availability of organs, only a few are actually transplanted.

The new treatment strategy for patients with many liver cysts was conducted by researchers from Radboud University Nijmegen Medical Centre, the Netherlands.

Hepatologist de Man R.A Drenth, professor at the Radboud University Nijmegen Medical Centre, commented: “In Nijmegen, we had experience with the administration of synthetic gastrointestinal hormones in two polycystic liver patients.”

“This treatment resulted in significantly smaller liver cysts. This stimulated us to proceed to a randomized clinical trial in 54 polycystic liver patients from Nijmegen (The Netherlands) and Leuven (Belgium), said a Radboud University release.

These findings were reported online in Gastroenterology.

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