Mother’s bone marrow could cure diseases in unborn babyJanuary 19th, 2011 - 3:40 pm ICT by IANS
London, Jan 19 (IANS) Scientists have developed a stem cell cure for deadly blood related diseases in unborn babies. Researchers extracted bone marrow cells from a pregnant mother and injected these into the developing foetus.
The donor cells were accepted by the foetus’s growing immune system without the need for any drugs, the Journal of Clinical Investigation reports.
The experiment carried out on animals is the first time that scientists have been able to successfully transplant a mother’s stem cells into her offspring before birth, according to the Daily Mail.
The technique could be used to treat a range of genetic diseases, including sickle cell anaemia or bubble boy disease, the immune system disorder that leaves babies vulnerable to normally harmless infections.
Tippi MacKenzie, who led the study at the University of California - San Francisco, said: “This research is really exciting because it offers us a straightforward, elegant solution that makes foetal stem cell transplantation a reachable goal.”
“We now, for the first time, have a viable strategy for treating congenital stem cell disorders before birth.”
Doctors say developing babies are ideal candidates for transplants because the risk of rejection is low and because they are less likely to need long-term drugs to suppress their immune systems.
However, most past attempts to transplant blood stem cells into a child in the womb have failed.
The new study found that a mother’s immune response prevents foetuses from accepting donor blood stem cells. When the researchers transplanted stem cells from the mother, the foetus accepted them.
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- Embryo's heartbeat drives formation of blood stem cell - May 14, 2009
- Stem cell transplant cheap in India, but very few centres - Jan 01, 2011
- How sickle haemoglobin protects against malaria - Apr 29, 2011
- Scientists figure out why foetus is not rejected - Jun 10, 2012
- Scottish scientists grow kidneys in lab - Apr 10, 2011
- Chhattisgarh to screen students for sickle cell anaemia - Apr 06, 2011
- 'Mini' transplant may safely reverse severe sickle cell disease in adults - Dec 10, 2009
- Mice study provides clues to curing blood diseases via prenatal cell transplantation - Aug 17, 2009
- Baby's genome lurks in mother's blood: Study - Dec 09, 2010
- Delhi doctors save Pakistani boy with stem cell transplant - May 24, 2010
- Baby's genome decoded from mom's blood, pop's saliva - Jun 07, 2012
- Clue to early diagnosis of pregnancy-related disease - May 16, 2012
- Technique to treat the donor larynx developed - May 01, 2011
- 'Chewing betel leaf may help fight cancer' - Sep 18, 2012
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