Men with Type 2 diabetes at risk of testosterone deficiency

March 16th, 2009 - 1:05 pm ICT by IANS  

London, March 16 (IANS) More than 50 percent of men with Type-2 diabetes are at risk of developing testosterone deficiency syndrome (TDS), more than double the rate in the non-diabetic population.
The symptoms are a drop in sex drive or libido, loss of energy, memory or concentration, negative moods, feelings of anxiety and feeling over-stressed.

TDS is associated with a 42 percent additional risk of developing Type 2 diabetes, and up to 60 percent additional risk of all-cause and coronary heart disease (CHD) mortality.

TDS, also known as hypogonadism, describes symptomatic patients with low serum testosterone levels. It is estimated to affect one in 10 men over the age of 50 years.

The data, presented by Geoff Hackett and endocrinologist Hugh Jones of Barnsley Hospital, reveal that TDS is associated with insulin resistance, raised HbA1c, visceral adiposity, raised BMI and ED, all of which are significant CHD risk factors.

Said Hackett, consultant in sexual medicine at Good Hope Hospital, Sutton Coldfield: “Testosterone Deficiency Syndrome is more common than GPs realise, particularly amongst men with Type 2 diabetes. Erectile dysfunction has been shown to be a robust predictor of CHD risk in men with Type 2 diabetes.”

TDS can be treated with testosterone therapy. Data presented reveal that testosterone therapy in hypogonadal diabetic men reduces insulin resistance and has beneficial effects on glycaemic control (regulation of blood glucose), waist circumference, leptin (protein hormone playing a key role in regulating energy intake) and energy expenditure, said a Good Hope release.

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