Embryo’s heartbeat drives formation of blood stem cellMay 14th, 2009 - 1:45 pm ICT by IANS
Washington, May 14 (IANS) Biologists have puzzled over why the heart begins beating so early in the foetus, before the tissues actually need blood infusion.
Two groups of researchers from Children’s Hospital Boston, Brigham and Women’s Hospital, and Harvard Stem Cell Institute (HSCI), presenting multiple lines of evidence from zebrafish, mice and mouse embryonic stem cells, provide an intriguing answer.
A beating heart and blood flow are necessary for development of the blood system, which relies on mechanical stresses to cue its formation.
Their studies offer clues that may help in treating blood diseases such as leukaemia, immune deficiency and sickle cell anaemia, suggesting new ways scientists can make the types of blood cells a patient needs.
This would help patients who require marrow or cord blood transplants, who do not have a perfect donor match, said a Children’s Hospital release.
These findings were published online by Cell and Nature Wednesday.
- New 'stretchy' technique generates 3 times more stem cells than usual - Oct 04, 2010
- Mother's bone marrow could cure diseases in unborn baby - Jan 19, 2011
- Embryo's heartbeat triggers blood stem cell formation - May 14, 2009
- New discovery may lead to more effective stem cell therapies for leukemia - Feb 15, 2010
- Sahara Hospital to start bone-marrow transplant - Sep 24, 2011
- Fish oil may hold key to leukaemia cure - Dec 23, 2011
- Stem cell transplant cheap in India, but very few centres - Jan 01, 2011
- Long-term pesticide exposure is harmful: STM study - Jun 20, 2012
- Turning diseased blood cells to stem cells may reveal cancer quickly - Feb 05, 2011
- Two units of umbilical cord blood 'reduce leukemia recurrence risk' - Nov 14, 2009
- New findings offer hope to patients with damaged kidneys - Feb 02, 2011
- Salman Khan to donate his bone marrow - Nov 14, 2010
- Umbilical cord cells may be useful in arthritis treatment - Nov 16, 2010
- Menstrual blood stem cells can treat many ailments - May 04, 2011
- Iraqi woman gets new life with bone marrow transplant in India - Sep 23, 2010
Tags: beating heart, biologists, blood diseases, blood flow, blood system, brigham and women, cord blood transplants, embryo, embryonic stem cells, foetus, heartbeat, hospital boston, hsci, immune deficiency, mechanical stresses, mouse embryonic stem cells, new ways, s hospital, stem cell, types of blood cells