The healing secret of human saliva revealedJuly 24th, 2008 - 1:07 pm ICT by ANI
Washington, July 24 (ANI): Licking your own wound can actually speed up the injurys healing process, according to group of researchers.
Scientists from the Netherlands say that a compound, which they have identified in human saliva, greatly speeds wound healing, according to their report published in The Journal of Federation of American Societies for Experimental Biology (FASEB).
The studys findings may offer hope to people suffering from chronic wounds related to diabetes and other disorders, as well as traumatic injuries and burns.
In addition, because the compounds can be mass-produced, they have the potential to become as common as antibiotic creams and rubbing alcohol.
“We hope our finding is ultimately beneficial for people who suffer from non-healing wounds, such as foot ulcers and diabetic ulcers, as well as for treatment of trauma-induced wounds like burns,” said Menno Oudhoff, first author of the report.
Specifically, scientists found that histatin, a small protein in saliva previously only believed to kill bacteria was responsible for the healing.
To come to this conclusion, the researchers used epithelial cells that line the inner cheek, and cultured in dishes until the surfaces were completely covered with cells.
Then they made an artificial wound in the cell layer in each dish, by scratching a small piece of the cells away. In one dish, cells were bathed in an isotonic fluid without any additions.
In the other dish, cells were bathed in human saliva. After 16 hours the scientists noticed that the saliva treated “wound” was almost completely closed. In the dish with the untreated “wound,” a substantial part of the “wound” was still open.
This proved that human saliva contains a factor, which accelerates wound closure of oral cells. Because saliva is a complex liquid with many components, the next step was to identify which component was responsible for wound healing.
Using various techniques the researchers split the saliva into its individual components, tested each in their wound model, and finally determined that histatin was responsible. (ANI)
- Licking your wounds may help them heal faster - Jul 24, 2008
- Promising new approach to treat diabetic wounds, chronic ulcers - Feb 09, 2011
- Newly-created bioactive peptides found to promote wound healing - Dec 08, 2010
- Scientists find enzyme family that plays crucial role in regulating cell motility - Mar 19, 2011
- Nano drug promising in treatment of chronic wounds - Feb 09, 2011
- Antibodies to speed up recovery from burns, ulcers - Jan 29, 2010
- Blast of sound can speed up wound healing - Nov 23, 2010
- Human umbilical cord blood cells accelerate diabetic wound healing - Feb 23, 2011
- Growth-factor-containing nanoparticles speed up healing of chronic wounds - Jan 27, 2011
- Stretchy patch could help repair wounded skin, damaged arteries - Apr 02, 2011
- Human stem cells from fat tissue successfully fuse with rat heart cells and beat - Mar 01, 2011
- Bone marrow cells that convert into skin cells could revolutionise wound treatment - Apr 05, 2011
- Level of depression determine healing rate of wounds among diabetics - Aug 03, 2010
- Zebra fish's self-healing could help spinal injury victims - Jun 03, 2012
- Receptor behind testosterone activity plays key role in wound healing - Jan 05, 2010
Tags: american societies, antibiotic creams, bacteria, burns, cells, cheek, chronic wounds, compounds, diabetic ulcers, dish, dishes, federation of american societies for experimental biolo, foot ulcers, healing process, healing wounds, human saliva, rubbing alcohol, traumatic injuries, wound closure, wound healing