Selenium may help in high-risk bladder cancer prevention
December 8th, 2008 - 1:20 pm ICT by ANIWashington, Dec 8 (ANI): A new study from Dartmouth Medical School has found that selenium, a trace mineral found in grains, nuts and meats, may help prevent high-risk bladder cancer.
The researchers found that women, moderate smokers and those with p53 positive cancer showed significant reductions in bladder cancer with higher rates of selenium.
The research involved 767 individuals with newly diagnosed bladder.
“There are different pathways by which bladder cancer evolves and it is thought that one of the major pathways involves alterations in the p53 gene,” said corresponding author Margaret Karagas, Ph.D., professor of community and family medicine of the Norris Cotton Cancer Centre at Dartmouth.
“Bladder cancers stemming from these alternations are associated with more advanced disease.
“Ultimately, if it is true that selenium can prevent a certain subset of individuals, like women, from developing bladder cancer, or prevent certain types of tumours, such as those evolving through the p53 pathway, from developing, it gives us clues about how the tumours could be prevented in the future and potentially lead to chemopreventive efforts,” said Karagas.
The study is published in Cancer Prevention Research, a journal of the American Association for Cancer Research. (ANI)
- Selenium may prevent high-risk bladder cancer - Dec 08, 2008
- How arsenic exposure triggers tumour growth - Feb 24, 2010
- Selenium intake linked to decreased risk of bladder cancer - Sep 01, 2010
- New approach for identifying smokers at highest lung cancer risk - Apr 08, 2010
- Immune system-suppressing drugs 'raise bladder cancer risk' - Oct 27, 2009
- Extra cheese could raise bladder cancer risk - Feb 09, 2011
- Biology of lung cancer in women dramatically different from men - Feb 10, 2010
- Parsley could help in breast cancer treatment - May 10, 2011
- Protein that makes local bladder cancer invasive found - May 15, 2010
- Scientists identify human body's natural defenses against cancer - Dec 12, 2009
- DNA damage can help protect the body from infection - Apr 01, 2011
- Mouse study shows nicotine does not promote lung cancer growth - Apr 05, 2011
- Restoring gene may slow spread of advanced lung tumours - Nov 25, 2010
- Genetic mutation linked to premature birth identified - Feb 02, 2010
- Smokers more vulnerable to bladder cancer - Nov 17, 2009
Tags: alterations, alternations, bladder cancer, bladder cancers, cancer centre, cancer prevention research, cancer research, dartmouth medical school, family medicine, grains, high risk, moderate smokers, norris cotton cancer, nuts, p53 gene, p53 pathway, pathways, subset, trace mineral, tumours
