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Washington, Nov 26 (ANI): Peoples perception of their pain depends on how they see the affected part of the body, says researchers, who discovered that by manipulating the appearance of a chronically achy hand, they could increase or decrease the ache and swelling in patients moving their symptomatic limbs.

In their opinion, the findings revealed a profound top-down effect of body image on body tissues.

“The brain is capable of many wonderful things based on its perception of how the body is doing and the risks to which the body seems to be exposed,” said G. Lorimer Moseley, who is now at the Prince of Wales Medical Research Institute in Australia.

In the study, the researchers asked ten right-handed patients with chronic pain and dysfunction in one arm to watch their own arm while they performed a standardized set of ten hand movements.

The participants repeated the movements under four conditions: with no visual manipulation, while looking through binoculars with no magnification, while looking through binoculars that doubled the apparent size of their arm, and while looking through inverted binoculars that reduced the apparent size of their arm.

As the patients” pain was always worse after movement than it was before, the extent to which the pain worsened depended on what people saw.

Specifically, the pain increased more when participants viewed a magnified image of their arm during the movements, andperhaps more surprisinglythe pain became less when their arm was seen through inverted binoculars that minimized its size.

The degree of swelling too was less when people watched a “minified” image of their arm during movements than when they watched a magnified or normal image, the researchers reported.

However, the researchers are not yet sure how this phenomenon works at the level of neurons.

But, they said that a possible philosophical explanation comes from the notion that protective responsesincluding the experience of painare activated according to the brain’’s implicit perception of danger level.

“If it looks bigger, it looks sorer and more swollen. Therefore, the brain acts to protect it,” said Moseley.

While he said the findings don”t mean that pain is any less real, they may lead to a new therapeutic approach for reducing pain. His team is now testing visual manipulations as an analgesic strategy for use in clinical settings.

The study is published in the latest issue of Current Biology, a Cell Press publication. (ANI)