Mechanism behind mind-body connection identified
July 16th, 2008 - 12:30 pm ICT by ANI ( Leave a comment )Washington, July 16 (ANI): A new study conducted by researchers at the University of California, Los Angeles (UCLA) provides fresh insights into the mind-body connection by finding how chronic emotional stress ages the immune system.
The researchers have found that the stress hormone cortisol suppresses immune cells” ability to activate their telomerase, enzymes that keep the cells young by preserving their ability to continue dividing.
They point out that every cell contains a tiny clock called a telomere, which shortens each time the cell divides.
According to them, short telomeres are linked to a range of human diseases, including HIV, osteoporosis, heart disease and aging.
Previous studies, says the research team, have shown that telomerase keeps immune cells young by preserving their telomere length.
The researchers insist that their latest study may help understand why the cells of persons under chronic stress have shorter telomeres.
The findings shed new light on how stress makes people more susceptible to illness, and also suggest a potential drug target for preventing damage to the immune systems of persons who are under long-term stress.
A research article describing the study says that this advancement offers new hope for caregivers to chronically ill family members, astronauts, soldiers, air traffic controllers, and people who drive long daily commutes.
“When the body is under stress, it boosts production of cortisol to support a “fight or flight” response,” says Rita Effros, professor of pathology and laboratory medicine at the David Geffen School of Medicine at UCLA, and a member of the Jonsson Cancer Center, Molecular Biology Institute and UCLA AIDS Institute.
“If the hormone remains elevated in the bloodstream for long periods of time, though, it wears down the immune system. We are testing therapeutic ways of enhancing telomerase levels to help the immune system ward off cortisol’’s effect. If we”re successful, one day a pill may exist to strengthen the immune system’’s ability to weather chronic emotional stress,” the researcher adds. (ANI)
- Chronic depression linked to accelerated immune cell aging - Apr 06, 2011
- Scientists unlock secrets of cancer-driving enzyme - May 08, 2011
- Physical activity may prevent stress on telomeres - Apr 05, 2011
- High levels of stress hormone in recovering alcoholics 'raise relapse risk' - Sep 24, 2010
- Stress speeds up breast cancer progression in mice - Sep 17, 2010
- Childhood abuse, adversity may shorten lifespan - Aug 15, 2010
- Medicinal plant may harbour HIV cure - Nov 11, 2008
- Experimental lung cancer drug may help treat brain, prostate cancer - Jan 04, 2010
- Simple spit and blood test could reveal if you're on the point of burnout - Feb 23, 2011
- 'All cancer cells are immortal' theory exposed as a myth - Apr 22, 2011
- Short DNA 'end-caps' linked to diabetes risk - Mar 25, 2011
- Laughter is good exercise for promoting health - Apr 28, 2010
- Loneliness 'ups risk of inflammatory diseases' - Feb 09, 2011
- Meditation training improves cellular health of the body - Nov 04, 2010
- Why drinking coffee cuts diabetes risk - Jan 14, 2011
Tags: air traffic controllers, chronic stress, david geffen school, david geffen school of medicine, david geffen school of medicine at ucla, drug target, emotional stress, flight response, human diseases, ill family members, immune cells, jonsson cancer center, long periods of time, molecular biology institute, stress hormone cortisol, telomere length, telomeres, term stress, ucla aids institute, university of california los angeles