Common intestinal bacteria may protect against diabetesOctober 7th, 2008 - 1:33 pm ICT by ANI
London, October 7 (ANI): A common intestinal bacteria can provide some protection against type 1 diabetes, according to a new study.
Research collaborators from Yale University and the University of Chicago say that their finding lends support to the “hygiene hypothesis” that exposure to an appropriate amount and composition of bacteria may be important to living a healthy life, and that diabetes and other autoimmune disorders may result from a lack of exposure to certain parasites and microbes.
While conducting experiments on mice, the researchers observed that exposure to certain bacteria would trigger an immune system response in the animals.
They said that the immune response they observed seemed to be what prevents autoimmune disorders, conditions where the immune system attacks healthy cells in the body.
In type 1 diabetes patients, the immune system attacks the beta cells in the pancreas, stopping a person’’s ability to detect glucose and produce insulin.
For their study, the researchers had used bacteria that are harmless microbes found in the human intestine.
Based on their observations, they came to the conclusion that safe, measured exposure to certain bacteria might lower the risk of immune disorders.
“This study outcome gives us a new avenue to explore,” Nature magazine quoted Dr. Richard A. Insel, Executive Vice President of JDRF, which funded the study, as saying.
“And, with type 1 diabetes in the U.S. and many countries around the world at about a three per cent annual rate, every lead is significant. The research gives impetus to better understanding how the bacterial flora in our body influences host immune defenses and responses that provide resistance to the development of type 1 diabetes. This understanding may provide new therapeutic approaches to prevention,” he added.
The researchers said their study involved such mice as would not develop diabetes under normal conditions. However, if raised in a germ-free environment, the mice developed diabetes, they added.
They said that the mice that were exposed to common intestinal bacteria maintained a lower risk for the disease. (ANI)
- Exposure to dirt in childhood promotes immunity - Mar 26, 2012
- Gut bacteria affect multiple sclerosis: Study - Jul 20, 2010
- Skin bugs protects body from infection - Jul 29, 2012
- Researchers cure type 1 diabetes in mice - Apr 09, 2010
- Scientists find 'knowing it in your gut' is real - Mar 24, 2011
- Mouth bugs, gum disease linked - Oct 28, 2011
- Prebiotic helps lower colon cancer risk: study - May 04, 2012
- Bacteria that may lead to inflammatory bowel disease identified - Sep 17, 2010
- Scientists use genetic approach to manipulate microbes in gut - Jun 25, 2010
- Is bacterial chatter behind mental illness, obesity? - Mar 24, 2011
- Cell population responsible for body's immune response identified - Mar 07, 2011
- Over cleanliness could wreck immune system! - Mar 23, 2012
- New discovery shows promise for type 1 diabetes treatment - Oct 06, 2010
- Stress hampers intestinal bacteria making immune system inactive - Apr 12, 2011
- Gut bug might trigger arthritis - Jun 18, 2010
Tags: autoimmune disorders, bacterial flora, beta cells, diabetes patients, dr richard, human intestine, hygiene hypothesis, immune defenses, immune disorders, immune response, immune system attacks, immune system response, intestinal bacteria, jdrf, microbes, nature magazine, research collaborators, therapeutic approaches, type 1 diabetes, yale university