Broad-spectrum antibiotics may give rise to drug-resistant super bugsAugust 27th, 2008 - 5:19 pm ICT by ANI
Washington, August 27 (ANI): University of Melbourne researchers suggest that doctors avoid prescribing expensive broad-spectrum antibiotics for pneumonia to avoid the development of more drug-resistant super bugs.
Dr. Patrick Charles, a PhD researcher and Austin Health Infectious Diseases consultant, says that only five per cent of people admitted to hospital with community-acquired pneumonia have infections caused by organisms that can not be successfully treated with the combination of penicillin and an “atypical” antibiotic, such as doxycycline or erythromycin.
He came to this conclusion after analysing samples of blood, urine, sputum and viral swabs of the nose and throat taken from 885 patients admitted to six Australian hospitals over 28 months from 2004 to 2006.
The study revealed that most cases of pneumonia were caused by easy to treat bacteria such as the pneumococcus or Mycoplasma, or alternatively by respiratory viruses that do not require antibiotic therapy.
“The study results show that current Australian guidelines for prescribing antibiotics for pneumonia are appropriate. It shows that Australian doctors should resist the push which is occurring in some parts of the world particularly the US - to prescribe broad spectrum antibiotics to treat essentially all possible causes,”” Dr. Charles said.
He said that the trend towards broad-spectrum antibiotics was being driven by laboratory-based studies, wherein the bacterial isolates would often come from highly selected patients with more difficult to treat disease.
He also highlighted the fact that the fear of litigation made some doctors unnecessarily opt for more aggressive treatments.
“The emergence of antibiotic-resistant bacterial pathogens is one of the biggest threats to Australian health care standards and is closely linked to the inappropriate use of antibiotics. By continuing to use more traditional antibiotics to treat most cases of pneumonia, Australian doctors can limit or delay the emergence of more resistant strains of bacteria,”” he said.
“By using the broad-spectrum antibiotics less often, we can also prolong the effective lifespan of these drugs. Furthermore, in the US, Canada and some parts of Europe, they are seeing some serious complications which appear to be related to the overuse of some classes of broad-spectrum antibiotics that are frequently used there to treat respiratory infections,” he added. (ANI)
- Broad spectrum drugs spur growth of resistant bugs - Oct 15, 2008
- Unique coating kills 99 percent bugs - May 11, 2012
- Simple antibiotics keep most super bugs at bay - Aug 27, 2008
- Pneumonia kills more children than any other disease - Nov 02, 2009
- Antibiotics ineffective against viral sinus infections - Mar 22, 2012
- Docs 'misuse' antibiotics when treating patients with respiratory infections - Sep 23, 2010
- Antibiotics named as 'greatest medical advance of last 50 years' - Nov 28, 2010
- Scientists identify new strategy to control antibiotic resistance - Mar 19, 2011
- Antibiotic dosing guidelines to help counteract superbugs - Jul 05, 2011
- New device to detect lung pathogens causing pneumonia - Feb 19, 2011
- Stress hampers intestinal bacteria making immune system inactive - Apr 12, 2011
- Deadly superbugs can come from animal farms too - Jan 26, 2011
- Antibiotic resistance spreads rapidly between bacteria: Study - Apr 12, 2011
- Dangerous new superbug targets young and healthy - Feb 19, 2012
- Peculiar 'sex' makes bacteria antibiotic resistant - Jun 12, 2009
Tags: antibiotics for pneumonia, australian doctors, australian health care, australian hospitals, bacterial pathogens, broad spectrum antibiotics, community acquired pneumonia, phd researcher, respiratory viruses, traditional antibiotics