Weight gain may increase breast cancer risk in postmenopausal womenNovember 14th, 2007 - 2:43 am ICT by admin
Obesity has been known to be a risk factor for developing breast cancer after menopause, as estrogens may accumulate in fat tissue, which has the potential of initiating or promoting the growth of cancerous cells, in the breast, which formed the basis of the study.
In the study 99,039 postmenopausal women participated.
In 1996, the women had reported their current body measurements and weight, plus their weight at ages 18, 35 and 50, in which Body mass index (BMI) was used to classify the participants as underweight, normal weight, overweight or obese.
By 2000, 2,111 of them had developed breast cancer.
In women who did not take menopausal hormone therapy, gaining weight in the early reproductive years (age 18 to 35), late reproductive years (age 35 to 50), perimenopausal and postmenopausal years (age 50 to the current age) and throughout adulthood (age 18 to the current age) were all linked to increased risk of developing breast cancer compared with maintaining a stable weight during those periods.
Women who were not obese or overweight at age 18 but were at ages 35 and 50 had 1.4 times the risk of developing breast cancer as compared with women who maintained a normal weight.
“Because weight gain during adulthood mainly reflects the deposition of fat mass rather than lean body mass, weight gain potentially represents age-related metabolic change that may be important in breast cancer development,” the researchers said.
“These findings may reinforce public health recommendations for the maintenance of a healthy weight throughout adulthood as a means of breast cancer prevention,” they added.
The analysis of the study found that women who had lost weight had the same breast cancer risk as those whose weight remained stable.
The study is issued in the Archives of Internal Medicine. (ANI)
- Smoking doesn't boost breast cancer risk in obese postmenopausal women - Apr 04, 2011
- Infants of obese mothers slow developers - Aug 07, 2012
- Avoidable breast cancer risk factors identified - Jan 19, 2011
- Gaining a pound a year after age 20 raises women's breast cancer risk - Apr 21, 2010
- Diet, exercise combination best way to lose weight - Apr 15, 2011
- Teenage obesity raises cancer risk - Jun 16, 2011
- Hot flushes tied to lower risk of breast cancer - Jan 26, 2011
- 10 tips to steer clear of breast cancer - Oct 03, 2010
- Smoking 'ups breast cancer risk in postmenopausal women' - Mar 02, 2011
- Estrogen helps women pile on pounds - Oct 06, 2011
- Smoking linked to increased risk of breast cancer - Jan 25, 2011
- 'Women hunched over desks for long gain weight' - Jul 11, 2012
- Taking tamoxifen to prevent breast cancer can save lives and cut medical costs - Mar 14, 2011
- Weight gain 'ups recurrence risk among breast cancer survivors' - Apr 06, 2011
- Starting hormone therapy at menopause 'ups breast cancer risk' - Jan 29, 2011
Tags: adulthood, age 18, bmi, body mass index, body measurements, breast cancer risk, cancer development, health recommendations, hormone therapy, increase breast, menopause, overweight, periods women, postmenopausal women, stable weight, weight gain