Researchers keep hepatitis C at bay after liver transplantJanuary 1st, 2010 - 5:02 pm ICT by IANS
Washington, Jan 1 (IANS) In most patients who undergo a liver transplant because of liver failure or liver cancer, the new liver becomes infected with the hepatitis C virus (HCV) almost immediately. But now researchers have developed an approach that transiently keeps HCV levels down in most HCV-infected patients receiving a new liver.
Hideki Ohdan, Kazuaki Chayama and colleagues at Hiroshima University in Japan, took immune cells known as lymphocytes from the donor livers before they were transplanted into the HCV-infected patients, activated them in0-vitro, and then injected them into the patients three days after they had received their liver transplants.
Importantly, these infused cells were able to keep HCV at bay even though the patients were taking immuno-suppressive drugs to prevent their immune systems from rejecting the new livers.
Despite showing clear clinical effects, the authors are planning further studies in which they will modify the protocol in an attempt to find a way to keep HCV levels down for longer and in all patients, says a Hiroshima release.
These findings were published in the Journal of Clinical Investigation.
- Hepatitis C vaccine undergoing trials - Aug 16, 2012
- New hope for patients with end-stage liver disease - Jan 12, 2011
- Coffee can cure hepatitis C - Jun 08, 2011
- New vaccine technology shows promise against hepatitis C virus - Feb 24, 2011
- 'Pep talk' can revive exhausted immune cells: Study - Dec 14, 2011
- New therapy could help beat Hepatitis C virus - Jan 17, 2012
- New approach could reverse liver failure - Aug 06, 2012
- Non-alcoholic steatohepatitis linked to liver cancer - May 26, 2010
- Iraqi woman gets new life with bone marrow transplant in India - Sep 23, 2010
- Integrate Hepatitis C testing with HIV: NGOs - Oct 21, 2011
- New antibody halts Hepatitis C infection - May 06, 2009
- Wrong treatment leads to Hepatitis C cases in China - Mar 03, 2012
- New generation of drugs to cure hepatitis C - Aug 14, 2010
- Hepatitis C: Cure and control, right now! - Jul 29, 2010
- Hepatitis C virus infection linked to fat enzyme in liver cells - Oct 11, 2010
Tags: colleagues, donor livers, further studies, hepatitis, hepatitis c, hepatitis c virus, hiroshima university, immune cells, immune systems, japan, journal of clinical investigation, liver cancer, liver failure, liver transplant, liver transplants, lymphocytes, protocol, suppressive drugs, vitro