New malaria vaccine shows promising results

November 14th, 2007 - 2:26 am ICT by admin  
The study finds that vaccine efficacy is 65 pct for a three-month period after infants were given three doses of the vaccine, and that it has a safety and tolerability profile.

It was also found that the vaccine reduced clinical illness due to malaria by 35 pct over a half-year period.

Though a large-scale Phase III study is essential to establish the efficacy of the vaccine, the results of the new study is encouraging.

The main objective of the study was to evaluate whether the vaccine should be cautiously administered for the age group more susceptible to malaria.

“We have shown for the first time that a vaccine can reduce the risk of malaria infection in young African infants exposed to intense P. falciparum transmission,” Lancet quoted CISM’s Pedro Alonso, MD, PhD, senior author of The Lancet article, principal investigator of the study, and head of the Barcelona Center for International Health Research (CRESIB) at the Hospital Clinic of the University of Barcelona, as saying,

“These tantalizing and unprecedented results further strengthen the vision that a vaccine may contribute to the reduction of the intolerable burden of disease and death caused by malaria,’ he added.

“We have invested over US$300 million in the development of this vaccine to make it as safe and effective as possible,” said Jean St

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