Microbubbles can deliver stroke drugs directly to brain
November 12th, 2010 - 1:04 pm ICT by IANSLondon, Nov 12 (IANS) Tiny bubbles of gas injected into the blood, can ease the passage of vital drugs to the brain and help protect it from the effects of a stroke.
Bubbles can even open up the blood-brain barrier, the protective blockade that regularly stops drugs from getting into the brain from the bloodstream.
Examples include the treatment of stroke, in which an interruption of the blood supply to the brain causes cells to become damaged or die.
Some years ago, scientists discovered that ‘microbubbles’ of air in the blood made ultrasound images clearer and brighter, reports the Daily Mail.
Now, researchers from the University of Cinncinnati, Ohio, US, filled microbubbles with xenon, a gas known to protect brain cells from dying and improve blood flow, but difficult to administer.
Rats treated with xenon-filled bubbles had smaller areas of brain damage than untreated animals, according to a university statement.
In another piece of research, bubbles filled with a drug used to break down clots, were used to treat people who had had strokes.
The technique eased the passage of the drug to the brain, speeding up the restoration of the blood flow to the brain.
But two of the patients given the highest dosage of the ‘bubble drug’ in combination with ultrasound started haemorrhaging and died.
Vibrating bubbles may even help break down tumours and kidney stones, scientists believe.
- Tiny bubbles 'could deliver stroke drugs directly into the brain' - Nov 12, 2010
- New device uses submarine technology to detect stroke quickly - Mar 30, 2011
- Drug from Indian spice builds brain cells after stroke - Feb 10, 2011
- New hybrid drug, derived from turmeric, may benefit stroke victims - Feb 10, 2011
- Human umbilical cord blood cells boost lab animal's recovery after stroke - Aug 25, 2010
- Key protein controlling blood vessel growth in mice's brain identified - Nov 12, 2010
- Cutting edge drug to protect brain from stroke - Mar 01, 2012
- Antibody cuts brain damage by 70pc in strokes - Jul 10, 2010
- Trojan Horse trick to deliver drugs into brains of stroke patients - Nov 11, 2010
- Delivering drugs directly to brain may help Alzheimer's sufferers - Mar 21, 2011
- New way to treat cancer using gas bubbles - Jun 28, 2010
- Pakistan hit by haemorrhagic strokes - Oct 31, 2011
- Natural vitamin E protects brain cells after stroke - Jul 06, 2011
- Cholesterol-lowering drugs may improve blood flow after stroke - Apr 27, 2011
- Erectile dysfunction drug could enhance delivery of herceptin to brain tumours - May 08, 2010
Tags: blockade, blood brain barrier, blood flow, blood supply to the brain, bloodstream, brain cells, brain damage, cinncinnati ohio, daily mail, interruption, kidney stones, stroke drugs, strokes, tiny bubbles, treatment of stroke, tumours, ultrasound images, university of cinncinnati, vital drugs, xenon