Greediness gene dooms dieting
November 15th, 2010 - 12:09 pm ICT by IANSLondon, Nov 15 (IANS) Your dieting resolve can be doomed if you are carrying a ‘greediness’ gene, a study shows.
Researchers have shown that a rogue gene linked to obesity makes us fat by boosting appetite.
This deep-seated drive to eat could also explain why so many of us succumb to temptation, no matter how strong our initial resolve to lose weight, according to the journal Nature Genetics.
The breakthrough opens the door for drugs that take the edge off appetite, melting away ‘muffin tops’ and pruning pot bellies, reports the Daily Mail.
Oxford University and the Medical Research Council researchers studied a gene called FTO, which when discovered in 2007, was the first gene to be linked with obesity.
Up to 14 percent of Britons carry two rogue copies of FTO, increasing their risk of obesity by 70 percent and diabetes by 50 percent. These people are, on average, almost half a stone heavier.
The 49 percent who have inherited just one flawed FTO gene are 30 percent more likely to be obese than those with two normal copies of the gene and 25 percent more likely to develop diabetes.
Scientists found that mice bred to have extra copies of the rogue gene were healthy, but ate more and became heavier than normal rodents.
Researcher Chris Church said: “For the first time, we have provided convincing proof that the FTO gene causes obesity.”
Prof Frances Ashcroft, one of the research leaders, said: “Too much activity of this gene can lead to putting on weight by overeating.”
- 'Greediness gene' causes diets to fail even before they start - Nov 15, 2010
- Exercise can undo effects of maternal obesity - Feb 10, 2012
- Lambs offer clues to why kids born to obese mums are fat - Mar 15, 2011
- Obesity gene can shrink the brain - Apr 20, 2010
- Blame your mom for your muffin top or thunder thighs - Oct 11, 2010
- Belly fat linked to development of asthma - Sep 26, 2011
- Blocking brain chemical burns fat even if you gorge - Mar 07, 2012
- 'Gluttony gene' forces you to gobble non-stop - Mar 19, 2012
- Experimental anti-obesity drug cuts body weight sans side effects - Jul 13, 2010
- Your shampoo could be making you fat - Jul 11, 2011
- Exercise can help fight 'obesity' gene - May 05, 2010
- Gene that regulates obesity and diabetes identified - Dec 15, 2009
- Beer belly or muffin top double mortality risk in heart disease patients - May 03, 2011
- Brain wiring makes women anorexic or obese - May 15, 2012
- Thin may get heavy if they socialise with obese - May 01, 2011
Tags: appetite, britons, convincing proof, daily mail, dooms, extra copies, frances ashcroft, fto gene, gene causes obesity, journal nature genetics, medical research council, mice, muffin tops, oxford university, pot bellies, putting on weight, research leaders, risk of obesity, rodents, rogue gene