Cutting calorie intake starves brain cancer

July 25th, 2010 - 5:47 pm ICT by IANS  

Washington, July 25 (IANS) Believe it or not, but reducing calorie intake can starve brain cancer to death.
Laura Shelton and colleagues from Boston College report success with mice suffering from the most aggressive and invasive form of primary human brain cancer, known as glioblastoma multiforme.

Restricting calorific intake lowers blood glucose levels and reduces the carbohydrate energy available to the tumour cells, which rely heavily on glycolysis, reports the journal ASN NEURO.

Glycolysis is a metabolic process that breaks down carbohydrates and sugars through a series of reactions and releases energy for the body, according to a college release.

The researchers said their findings indicate that brain tumour cells are more sensitive to energy stress than normal brain cells and can be targeted through principles of metabolic control theory.

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