A compound for healing painful blisters
April 25th, 2011 - 1:47 pm ICT by IANSWashington, April 25 (IANS) Researchers have identified a compound that shows promise in healing painful blisters known as shingles, not amenable to treatment so far.
Most adults remember the fever, itchy blisters and possibly tiny scars they experienced as children when they had chickenpox, which is caused by the varicella-zoster virus, or VZV.
Unfortunately, that memory can come back when they are older. The VZV virus from childhood chickenpox hides in the nerves, emerging most frequently in adults over the age of 60 as a blistering rash on one side of the body, reports the American Journal of Preventive Medicine.
The rate of complications, including nerve pain that can persist for months or years after the shingles attack is gone, also increases with age. The novel and effective anti-shingles agent, called L-BHDA, may change that.
“We need new options for medications with increased potency and specificity that can treat VZV, including strains that may be resistant to existing drugs,” said Chung (David) Chu, professor in pharmaceutical and biomedical sciences at the University of Georgia, according to a Georgia statement.
“L-BHDA has the potential to be more effective than existing agents,” said Chu. He noted that the new compound has been tested in the lab and demonstrated in mice models by a group of researchers headed by Jennifer Moffat, associate professor of microbiology and immunology at the State University of New York Upstate Medical University.
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- Scientists link shingles susceptibility to family history - May 20, 2008
- Chicken pox hits 90 kids in South Africa - Sep 22, 2010
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- Breakthrough could protect people at risk from pain of shingles - Jun 09, 2010
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- Quick vaccination cuts risk of chickenpox after exposure - Jan 21, 2010
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Tags: american journal of preventive medicine, biomedical sciences, blistering rash, chickenpox, david chu, journal of preventive medicine, microbiology and immunology, moffat, nerve pain, painful blisters, potency, shingles, specificity, state university of new york, state university of new york upstate medical university, tiny scars, university of georgia, upstate medical university, varicella, varicella zoster virus