Vitamin C may help prevent gout in menMarch 10th, 2009 - 1:34 pm ICT by ANI
Washington, Mar 10 (ANI): Men who consume higher levels of vitamin C are less likely to develop gout, a painful type of arthritis, says a new report.
“Gout is the most common type of inflammatory arthritis in men,” the authors write as background information in the report in the March 9 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
“Epidemiologic studies suggest that the overall disease burden of gout is substantial and growing. The identification of the risk factors for gout that are modifiable with available measures is an important first step in the prevention and management of this common and excruciatingly painful condition,” they added.
To reach the conclusion, Hyon K. Choi, M.D., Dr.P.H., then of University of British Columbia, Vancouver, and now of Boston University School of Medicine, and colleagues examined the relationship between vitamin C intake and gout in 46,994 men between 1986 and 2006.
Every four years, the men completed a dietary questionnaire, and their vitamin C intake through food and supplements was computed. Every two years, participants reported whether they had been diagnosed with or developed symptoms of gout.
During 20 years of follow-up, 1,317 men developed gout. Compared with men who had a vitamin C intake of less than 250 milligrams per day, the relative risk of gout was 17 percent lower for those with a daily intake of 500 to 999 milligrams, 34 percent lower for those with an intake of 1,000 to 1,499 milligrams per day and 45 percent lower for those with an intake of 1,500 milligrams per day or higher.
For every 500-milligram increase in their vitamin C intake, men’’s risk for gout appeared to decrease by 17 percent.
Compared with men who did not take vitamin C supplements, those who took 1,000 to 1,499 supplemental milligrams per day had a 34 percent lower risk of gout and those who took 1,500 supplemental milligrams per day had a 45 percent lower risk.
Vitamin C appears to reduce levels of uric acid in the blood, the authors note; a buildup of this naturally occurring compound can form crystal deposits in and around joints, leading to the pain, inflammation and swelling associated with gout.
Vitamin C may affect reabsorption of uric acid by the kidneys, increase the speed at which the kidneys work or protect against inflammation, all of which may reduce gout risk, the authors note.
“Given the general safety profile associated with vitamin C intake, particularly in the generally consumed ranges as in the present study (e.g., tolerable upper intake level of vitamin C of less than 2,000 milligrams in adults according to the Food and Nutrition Board, Institute of Medicine), vitamin C intake may provide a useful option in the prevention of gout,” they conclude. (ANI)
- Vitamin C intake could lower risk of gout in men - Mar 10, 2009
- CT scans can detect gout cases - Nov 07, 2011
- Orange juice doubles gout risk in women - Nov 11, 2010
- Sweetened drinks up risk of gout in women: Study - Nov 08, 2010
- Gout ups risk of heart attacks among women - Feb 08, 2010
- Tart cherries may reduce inflammation, risk factors for heart disease - Apr 13, 2011
- Vitamin E lowers liver cancer risk - Jul 19, 2012
- Low vitamin C levels elevates heart failure risk - Nov 14, 2011
- Eating foods rich in vitamin E 'lowers dementia risk' - Jul 13, 2010
- Four cups of coffee a day keeps gout from women at bay - Sep 10, 2010
- Meta-analysis shows folic acid supplements not beneficial for heart - Oct 12, 2010
- Fibre intake lowers death risk - Feb 15, 2011
- Caffeinated drinks linked to increased risk of gout attacks - Nov 08, 2010
- Regular soda intake spikes stroke risk - Apr 22, 2012
- Arthritis invites higher risk of heart attacks - Mar 09, 2012
Tags: 500 milligrams, archives of internal medicine, background information, boston university school, boston university school of medicine, british columbia vancouver, disease burden, epidemiologic studies, gout, inflammatory arthritis, jama, milligram, relative risk, risk factors, school of medicine, symptoms of gout, university of british columbia, university of british columbia vancouver, vitamin c intake, vitamin c supplements