Use of antidepressant linked to reduction in menopausal hot flashesJanuary 19th, 2011 - 5:15 pm ICT by ANI
Washington, Jan 19 (ANI): A new study has suggested that the use of antidepressant medication reduces the frequency and severity of hot flashes in menopausal women.
Ellen W. Freeman, of the University of Pennsylvania School of Medicine, Philadelphia, and colleagues evaluated the efficacy of escitalopram vs. placebo to reduce the frequency and severity of hot flashes in healthy women, and examined whether race, menopausal status, depressed mood, and anxiety were important modifiers of any observed effect.
The multicenter, 8-week, randomized trial enrolled 205 women between July 2009 and June 2010.
The average frequency of hot flashes at the beginning of the study was 9.8 per day. Escitalopram was associated with a significant reduction in the frequency of hot flashes relative to placebo, adjusted for race, site, and baseline hot flash frequency.
In the escitalopram group, average hot flash frequency at week 8 decreased to 5.26 hot flashes per day. In the placebo group, hot flash frequency decreased to 6.43 hot flashes per day.
Clinical improvement at week 8 was significantly greater in the escitalopram group than in the placebo group. Also, use of escitalopram significantly reduced hot flash severity compared with placebo, adjusted for race, site, and baseline severity.
The researchers noted that although the decreases in hot flash frequency and severity appeared modest, the study participants perceived these improvements as meaningful, as indicated by their reported satisfaction with treatment and desire to continue the treatment.
The findings were reported in the journal JAMA. (ANI)
- Flaxseed no cure for hot flashes during menopause - Jun 06, 2011
- Soy-based supplement reduces menopausal hot flashes - Oct 07, 2010
- Menopausal women could 'work out' hot flashes - Jun 29, 2012
- Acupuncture reduces severity of menopausal hot flushes - Mar 08, 2011
- Religious young adults 'more likely to become obese by middle age' - Mar 25, 2011
- Weight loss program improves hot flushes in obese menopausal women - Jul 13, 2010
- Soy-based compound in dietary supplement could cut menopausal hot flushes - May 01, 2010
- Taking tamoxifen to prevent breast cancer can save lives and cut medical costs - Mar 14, 2011
- Menopausal hot flashes 'may protect women's hearts' - Feb 25, 2011
- Iron supplements lower fatigue in non-anaemic women - Jul 10, 2012
- Losing Weight Can Cool Hot Flashes, Researchers Say - Aug 29, 2010
- Nerve pain pill found effective in treating hot flashes - May 16, 2009
- 'Cool' imagery lowers hot flashes in women nearing menopause - Jul 18, 2010
- Exercise, attitude may influence hot flashes - Apr 15, 2012
- Weight loss helps boost low testosterone levels - Jun 26, 2012
Tags: antidepressant, clinical improvement, decreases, depressed mood, escitalopram, flash frequency, hot flash, jan 19, journal jama, menopausal hot flashes, menopausal women, modifiers, pennsylvania school, placebo group, randomized trial, school of medicine, severity, study participants, university of pennsylvania, university of pennsylvania school of medicine