Taste genes predict dental caries
September 23rd, 2010 - 5:15 pm ICT by ANIWashington, Sep 23 (ANI): A new study has hypothesized that genetic variation in taste pathway genes (TAS2R38, TAS1R2, GNAT3) may be associated with dental caries risk and/or protection.
According to researchers from University of Pittsburgh and West Virginia University, dental caries occurrence and progression is known to be influenced by a complex interplay of both environmental and genetic factors, with numerous contributing factors having been identified including bacterial flora, dietary habits, fluoride exposure, oral hygiene, salivary flow, salivary composition, and tooth structure.
In this study, families were recruited by the Center for Oral Health Research in Appalachia (COHRA) for collection of biological samples, demographic data and clinical assessment of oral health including caries scores.
Multiple single nucleotide polymorphism (SNP) assays for each gene were performed and analyzed using transmission disequilibrium test (TDT) analysis (FBAT software) for three dentition groups: primary, mixed, and permanent. Statistically significant associations were seen in TAS2R38 and TAS1R2 for caries risk and/or protection.
The article has been published in the Journal of Dental Research titled “Taste Genes Associated with Dental Caries”. (ANI)
- How did the giant panda lose its taste for flesh? - Dec 06, 2010
- Sauce tempts kids into eating more greens - Dec 02, 2011
- Substantial consumption of fluoride ups chance of mild fluorosis - Oct 26, 2010
- Enzyme in saliva influenceshow we sense food texture - Oct 14, 2010
- Black tea has more fluoride than once thought! - Jul 15, 2010
- Neanderthals could taste bitter flavors just like modern humans - Aug 12, 2009
- Drinking too much tea 'can cause bone problems' - Jul 15, 2010
- Oral vaccines are 'alternative to jab' - Feb 11, 2011
- Scientists clue in on why saliva glands stop working - Jun 03, 2011
- Fluoride in water good for dental health - Aug 25, 2010
- Genetic deletion identified as major risk factor for autism, schizophrenia - Nov 05, 2010
- Your genes help you pick your friends: Study - Jan 18, 2011
- Europeans are world's most sugar-sensitive people - Jun 27, 2009
- Gene that predisposes people to syndrome with high cancer risk identified - Dec 22, 2010
- Most people brush their teeth the wrong way - May 16, 2012
Tags: appalachia, assays, bacterial flora, biological samples, caries risk, clinical assessment, demographic data, dentition, dietary habits, genetic factors, genetic variation, journal of dental research, nucleotide polymorphism, oral health research, oral hygiene, salivary flow, snp, study families, tooth structure, west virginia university