Study sheds new light on genetics of schizophreniaMarch 20th, 2009 - 2:57 pm ICT by ANI
Washington, Mar 20 (ANI): A new study, conducted by researchers at University of Edinburgh, has shed new light on the genetics of mental illnesses such as schizophrenia and bipolar disorder.
The researchers found that a gene called DISC1 known to play a role in the development of mental illness may control the way some patients respond to psychiatric medication.
They also identified seven proteins that are important to the development of mental illness and hope the research could help to create new medicines that target these proteins.
The research was based on existing data from the Human Genome Project, a pioneering study, which mapped all the genes in human DNA.
The team analysed variations of the DISC1 gene and found that it affects a number of other genes that current medications are designed to target.
They believe that by identifying those patients in whom DISC1 may be a root cause of illness, they could find the patients for whom these drugs would be most effective.
“We know that disorders such as schizophrenia have a genetic element and that this specific gene, DISC1, is important to that process. This research helps us to understand exactly how it affects brain development and provides clues about how to solve problems when that process goes wrong,” Dr. William Hennah, who led the project at The University of Edinburgh and is now based at the Finland Institute for Molecular Medicine, said.
The results are published in the Public Library of Science One. (ANI)
- Scientists identify genetic link to suicidal behaviour - Oct 09, 2011
- Immunologists rule out virus' role in mental illness - Feb 01, 2012
- Researchers identify gene linked to schizophrenia - Dec 16, 2009
- 'Mental illness' gene identified - Nov 26, 2009
- Genes trigger roots of bipolar disorder? - Sep 02, 2012
- Potential therapeutic target for schizophrenia identified - Feb 24, 2011
- Schizophrenia genes linked to brain signalling - May 11, 2010
- Unusual genes behind schizophrenia identified - Jul 11, 2011
- Study finds gene mutation strongly linked to schizophrenia - Feb 03, 2011
- Scientists identify genetic link to suicide attempts - Mar 29, 2011
- Babies born in spring 'more likely to develop anorexia nervosa' - Apr 28, 2011
- Genetic variations linked to schizophrenia, bipolar disorder - Jul 02, 2009
- Previously unrecognized susceptibility factor for bipolar disorder identified - Mar 04, 2011
- Gene that can influence a person's risk for developing epilepsy identified - Apr 05, 2011
- Lower enzyme levels linked with schizophrenia - Jul 21, 2011
Tags: bipolar, brain development, disc1 gene, dr william, genes, genetic element, genetics of schizophrenia, hennah, human dna, human genome project, mental illness, mental illnesses, molecular medicine, new medicines, proteins, psychiatric medication, public library of science, root cause, schizophrenia, university of edinburgh