Sticky mussels inspire tough coating for living cells

April 7th, 2011 - 6:25 pm ICT by ANI  

Washington, April 7 (ANI): Mussels’ ability to stick to a wide variety of objects is well known.

Now inspired by this, scientists have developed a protective coating with the potential to enable living cells survive in a dormant condition for long periods despite intense heat, dryness and other hostile conditions.

They liken the coating to the armour that encloses the spores that protect anthrax and certain other bacterial cells, making those microbes difficult to kill.

Insung S. Choi and colleagues said their simple method for coating the yeast cells could ’serve as a new strategy for controlling cell division and protection of artificial spore like structures in a designed way’.

The technique could be used to encapsulate individual cells for a variety of purposes, including the creation of tiny chemical probes, single-cell chemical factories, and perhaps armour for transplanted cells used in anti-cancer therapies.

The new coating is an organic material called polydopamine, chemically similar to mussel adhesive.

In laboratory experiments, the coating slowed down cell division in the yeast, while protecting them from cell-digesting chemicals.

“We believe that polydopamine encapsulation would be a good starting point for both fundamental research and applications based on artificial spores, as it endows living cells with durability against harsh environments, controllability in cell cycles, and reactivity for cell-surface modification,” said the researchers.

The finding appears in a report in Journal of the American Chemical Society. (ANI)

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