Soybean may help cut menopause effectsApril 9th, 2009 - 12:34 pm ICT by ANI
Washington, Apr 9 (ANI): Soy aglycons of isoflavone (SAI), a group of soybean constituent chemicals, may help reduce menopause effects, say researchers.
The research, described in BioMed Central’s open access journal Nutrition & Metabolism, shows how dietary supplementation with SAI lowers cholesterol, increases the anti-oxidative properties of the liver and prevents degeneration of the vaginal lining.
Robin Chiou led a team of researchers from National Chiayi University, Taiwan, who studied the effects of the dietary supplement on a group of female rats that had undergone ovary removal.
He said, “These ovariectomized animals are a good model for study of the menopause as the loss of oestrogen from the ovaries mimics the natural reduction in oestrogen seen in menopausal women. SAI itself has weak oestrogenic properties and we’ve shown here that menopause-related syndromes can be prevented or improved by dietary supplementation with the compounds it contains”.
In comparison to control animals, the authors found that the ovariectomized rats fed a diet enriched with SAI showed increased liver antioxidative activities and improved lipid profiles. Levels of harmful LDL cholesterol were reduced, while beneficial HDL cholesterol was increased.
According to Chiou, “It is generally agreed that the higher HDL and the lower LDL concentrations are of benefit in chemoprevention of cardiovascular diseases. Our findings support the indication that soybean consumption may prevent coronary heart disease”.
The authors hope that dietary soy supplementation may provide an alternative to hormone replacement therapy (HRT), which has been linked to the development of uterus and breast cancers. (ANI)
- Soy beats milk in cholesterol lowering: Study - Jan 19, 2011
- Soy 'ups radiation's ability to destroy lung cancer cells' - Apr 02, 2011
- Soybean could boost bone health: Study - Jul 31, 2010
- Soy intake lowers breast cancer recurrence in hormone-sensitive cancers - Oct 19, 2010
- Adding monounsaturated fats to diet 'improves cholesterol levels' - Nov 02, 2010
- Soyfoods protect against breast cancer, lower cholesterol - Dec 03, 2010
- High soy intake reduces risk of breast cancer - Jun 15, 2010
- Dietary soy may affect risk of breast cancer - Nov 09, 2010
- Antioxidant protein promotes clogging of arteries, says study - Jan 11, 2011
- Soy-based supplement reduces menopausal hot flashes - Oct 07, 2010
- Consume lots of soy to reduce breast cancer risk (Lead) - Jun 15, 2010
- Bile pigment could stave off cancer, heart disease - Jun 26, 2012
- Scientists find cholesterol regulating 'remote-control' in brain - Jun 07, 2010
- Soy protein can lower fat accumulation in liver - Apr 23, 2012
- Dietary supplements may not halt bone loss - Sep 03, 2009
Tags: biomed central, breast cancers, cardiovascular diseases, chemoprevention, chiayi, chiou, coronary heart disease, dietary supplementation, female rats, harmful ldl cholesterol, hdl cholesterol, hormone replacement therapy, isoflavone, journal nutrition, lipid profiles, menopausal women, oestrogen, ovariectomized rats, ovaries, soybean consumption