Scientists one step closer to universal flu vaccine
October 22nd, 2010 - 12:00 pm ICT by ANILondon, Oct 22 (ANI): Researchers at Scripps Research Institute in la Jolla, California, teamed up with Peter Palese and colleagues at Mount Sinai Medical
School in New York to test a protein that works against viruses from every flu family that attacks people.
These included three pandemic viruses (H1, H2 and H3), three others that attack occasionally (H6, H9 and H7), and the H5N1 bird flu from 2004 - albeit
modified to make it less deadly.
Mice were injected with this protein twice, three weeks apart, to allow their immunity to develop. Two weeks after the second injection each mouse was
exposed to one type of live flu virus, as were unvaccinated mice, reports New Scientist.
Vaccinated mice still became ill, but not as ill as unvaccinated mice, judging from the weight they lost, a standard measure of illness in mice.
Despite partial protection, the vaccine would be cheap and quick to make, and could stop people dying, the team say - which might be enough in a serious
pandemic.
However, since it doesn’t prevent illness altogether, people would still need constant re-vaccination to avoid ordinary, seasonal flu.
Swine flu seems to have replaced one formerly common flu virus, from its own H1 family, and it dominated the Australian flu season. But the most deadly
pre-pandemic virus, H3N1, remains common in China, south-east Asia and Africa, and has accounted for half the US cases tested this season.
If we could identify a flu protein that the virus can’t alter so readily, then we should be able to elicit immunity that recognises all kinds of flu.
The study was published in Proceedings of the National Academy of Sciences. (ANI)
- 2009 H1N1 pandemic influenza vaccine protects mice from 1918 flu virus - Jun 16, 2010
- H1N1 pandemic flu strain 'key to universal vaccine' - Jan 11, 2011
- Cuba to give flu shots to over 600,000 people - Nov 20, 2011
- Swine flu spread much wider than suspected - Jun 09, 2011
- The reason behind mildness of 2009 H1N1 pandemic - Jun 19, 2010
- Scientists review fate of pandemic H1N1 flu virus - Sep 29, 2010
- Novel vaccine that produces strong immunity against cocaine high created - Jan 05, 2011
- Mexican swine flu outbreak kills 29, infects nearly 1,500 - Jan 28, 2012
- Swine flu shot may hasten sleeping disorder - Mar 29, 2012
- Maternal influenza vaccination linked to flu protection in infants - Oct 05, 2010
- Now, a 'universal' vaccine that could fend off all types of flu - Jul 16, 2010
- Obese more vulnerable to flu - Oct 26, 2011
- Nasal spray flu vaccine one step closer - Feb 18, 2011
- Universal influenza vaccine 'on the anvil' - Dec 07, 2010
- 1976 swine flu immunization might protect against pandemic H1N1 virus - Apr 24, 2010
Tags: bird flu, flu season, flu vaccine, flu virus, h1 h2, h5n1 bird flu, h7, h9, la jolla, mount sinai medical, mount sinai medical school, national academy of sciences, new scientist, palese, pandemic, proceedings of the national academy, proceedings of the national academy of sciences, scripps research institute, south east asia, swine flu