Salmonella from space providing clues to making food poisoning vaccine

April 16th, 2009 - 12:08 pm ICT by ANI  

Australia, Apr 16 (ANI): Analysing a batch of bacteria brought back by the shuttle Discovery crew last month, scientists could soon develop a vaccine against food poisoning from salmonella bacteria.

The researchers conducted a series of experiments aboard the International Space Station, and are now working to develop compounds for a salmonella vaccine

While previous studies showed that salmonella could become more virulent in weightlessness, further research proved that its virulence could be controlled, toggled on and off like a switch.

Station program scientist Dr. Julie Robinson has revealed that studies in this regard began only because NASA feared that its astronauts could be more susceptible to food poisoning in space due to their weakened immune systems, resulting from microgravity.

Later, the researchers found that microgravity changes salmonella itself, which could provide insight into a new way to possibly control the bacteria on earth.

“Given that salmonella is among the leading causes of food-borne pathogens, one of the disappointments of the 21st century is that we don’t have a vaccine,” ABC Science quoted Arizona State University’s Dr Cheryl Nickerson as saying.

Nickerson heads one of the research teams investigating salmonella in space, which identified genetic changes in space-borne salmonella that made the bacteria more virulent than identical samples on earth.

And as the environment inside the intestines is similar to weightlessness, the researchers believe that the study could give rise to a vaccine and other treatments for food poisoning.

Last year, a second series of salmonella investigations flew aboard the space station.

Led by Professor Timothy Hammond at the Durham Veterans Administration Medical Center in North Carolina, the research is aimed at developing a vaccine based on the genetic changes seen in the space-borne bacteria. (ANI)

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