Resistance exercise-blood flow restriction combo boosts muscle mass in elderly

May 15th, 2010 - 3:03 pm ICT by ANI  

Washington, May 15 (ANI): Researches have found that combining low resistance exercises with restriction of blood flow through body parts may boost muscle build-up in the elderly.

Many older people are unable to get the full benefits of weightlifting and other exercises because they suffer from conditions such as arthritis that prevent them from lifting enough weight to stimulate muscle growth.

University of Texas Medical Branch at Galveston researchers have determined that moderately and temporarily restricting the flow of blood through muscles can be combined with low-level resistance exercise training to produce muscle-mass increases in older men.

This is a practice adopted by bodybuilders who noticed that it made light weights feel heavier.

“We think that this may be a novel treatment for older people who need to bring their muscle mass back up,” said UTMB physical therapy professor Blake Rasmussen, senior author of a paper on the investigation (”Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men”) appearing in the May issue of the Journal of Applied Physiology. “It could also be used for patients who have had surgery and aren’t capable of lifting enough weight to keep their muscles in shape, or for people who have arthritis or other conditions that make lifting heavy weights a problem.”

A simple experiment that demonstrated the above theory was carried out in seven men with an average age 70.

“We saw that when we put the cuffs on, they responded similarly to young people doing traditional high-intensity resistance exercise,” said UTMB graduate student Christopher Fry, the lead author of the paper. “The low-intensity exercise produced increases in protein synthesis, and activated two cellular pathways that stimulate protein synthesis and muscle growth in the post-exercise period.”

Rasmussen and Fry speculated that either an improved ability to activate Type II muscle fibers or a response to the sudden surge of blood into the muscles when the cuffs were released could be responsible for this result. Whatever the mechanism, Rasmussen said, “we think it’s an exciting potential new rehabilitation tool.”

“You could use this following ACL knee surgery or hip fracture surgery, for example,” Rasmussen said. “In the first few weeks after ACL surgery, the joint just won’t allow you to lift heavy weight. So instead, you could use a really light weight with a restriction cuff, which may prevent the muscle loss that you normally see following knee surgery.”

This study appears in the May issue of the Journal of Applied Physiology. (ANI)

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