Rat lungs renovated in lab using stem cells
June 25th, 2010 - 2:48 pm ICT by ANIWashington, June 25 (ANI): Scientists from Yale University have discovered a novel technique that uses stem cells to build better lungs.
According to the researchers, ‘reseeding’ lungs with a patient’s own stem cells before a transplant could save millions of lives.
The researchers have come up with a technique to remove all cells from a lung and then reseed the remaining connective tissue scaffold with a patient’s own cells.
“This is really the first paper that talks about engineering an entire lung that can be implanted and can exchange gas,” Discovery News quoted Laura Niklason, a scientist at Yale University and a co-author on the Science paper, as saying.
Currently scientists are experimenting with rats and not humans.
Lung transplants are usually risky procedures, but if a patient’s own stem cells re-colonized the lung, the chance of organ rejection would drop dramatically, which should raise the long-term survival rate.
Conducting the experiment on rats’ lungs, the scientists found that the reseeded lungs worked just as the original lungs.
However, there are hurdles that the scientists need to clear before the procedure is tried on humans. They are high on optimism, though.
Kidneys, liver, hearts and other organs could all potentially be reseeded with a patient’s own cells, which are grown and then implanted into the patient to eliminate organ rejection.
“No one expected this to work so well, not even for a short amount of time,” said Daniel Weiss, a scientist at the University of Vermont.
“This research will set the stage for years to come.” (ANI)
- Scientists Grows Rat Lung In Laboratory, Calls It An Achievement In Lung Treatment - Jun 26, 2010
- Scientists implant regenerated lung tissue in rats - Jun 25, 2010
- Scientists grow human heart in lab - Apr 04, 2011
- Scottish scientists grow kidneys in lab - Apr 10, 2011
- Scientists grow human bones from fat - Jun 10, 2012
- Technique to treat the donor larynx developed - May 01, 2011
- Artificial lungs offers hope to transplant patients - Jul 15, 2010
- Live human heart grown in lab offers new hope to cardiac patients - Apr 04, 2011
- Scientists Again Grow The Lung Of A Rat In A Laboratory - Jun 26, 2010
- New research offers hope to Parkinson's disease patients - Feb 09, 2011
- Hope for baldness cure - Apr 30, 2012
- Cross blood group transplants conducted in India - Nov 11, 2011
- Stem cells help women regrow breasts after surgery - Feb 20, 2011
- Scientists focus on human cells for spinal cord injury repair - Mar 03, 2011
- Stem cells from skin, blood regenerate faltering liver - May 12, 2011
Tags: co author, connective tissue, daniel weiss, discovery news, gas discovery, hurdles, kidneys, lung transplants, lungs, novel technique, optimism, organ rejection, rats, scaffold, science paper, stem cells, survival rate, term survival, university of vermont, yale university