Rapid transition through menopause linked to early heart disease onsetJanuary 28th, 2009 - 3:00 pm ICT by ANI
Washington, Jan 28 (ANI): Women who transition more quickly through menopause are at increased risk for a higher rate of progression of “preclinical atherosclerosis” narrowing of arteries caused by the thickening of their walls, concludes a new study.
Cardiologist C. Noel Bairey Merz, M.D, led the multifaceted Los Angeles Atherosclerosis Study (LAAS), in which 203 women between ages 45 and 60 were evaluated.
While fifty-two women were premenopausal, 20 were perimenopausal and 131 were postmenopausal, none of them had been diagnosed with cardiovascular disease.
They were evaluated when they entered the study and at two 18-month intervals, providing a snapshot over a three-year period of time.
Evaluations included carotid intimal-media thickness (cIMT) measurements and objective measures of menopausal status based on hormone levels and physiologic changes, not subjective factors, such as hot flashes and estimates of menstrual cycling.
It was found that women who transitioned from being premenopausal to being fully postmenopausal within three years had more build-up of fatty plaque in their carotid arteries.
Thus the researchers suggested that women who transition through menopause rapidly are at greater risk of early development of heart disease.
“We know that more fatty plaque accumulation predicts future heart attacks and strokes, but this is our first venture into this particular line of inquiry. This is an observational study, which doesn”t provide specific recommendations for patient evaluation and treatment, but it does raise questions,” said Bairey Merz.
She added: “The findings suggest that we study this more definitively to possibly determine if women undergoing a more rapid menopause might benefit from early hormone replacement therapy.
“In the meantime, physicians could consider using carotid intimal-media thickness measurement or other cardiovascular screenings for women who are rapidly transitioning or who have certain risk factors, such as cigarette smoking or chemotherapy, which are known to accelerate transition through the menopause.”
However, she cautioned that patients should not use the study to self-diagnose or presume they may be at higher risk because of symptoms. (ANI)
- Post-menopause, women more vulnerable to heart attacks - Jun 12, 2012
- Oral contraceptives thought safe can carry long-term risks - Jan 16, 2009
- New technique to identify potential atherosclerosis risk found - Apr 12, 2011
- Intake of egg yolks can block arteries: Study - Aug 14, 2012
- Sex hormone protects women from cardio risks - Aug 12, 2011
- Body fat distribution linked to a higher risk of ER-negative breast cancer - Dec 16, 2010
- High fat diet damages arteries earlier than suspected - Apr 04, 2012
- Low-carb, low-fat and Mediterranean diets 'reverse atherosclerosis in fat people' - Mar 02, 2010
- Weight loss diets reverse arterial clogging - Mar 03, 2010
- Aggressive people 'have higher heart attack risk' - Aug 17, 2010
- Menopause not linked to heart attack - Sep 06, 2011
- Hormone therapies 'up breast cancer metastasis risk in post-menopausal women' - May 07, 2010
- People with sleep apnea 'more likely to develop aggressive heart disease' - Dec 01, 2010
- Yoghurt consumption curbs heart disease - Oct 24, 2011
- Ultrasound technique better alternative to invasive angiography for diagnosing heart disease - Jun 15, 2010
Tags: atherosclerosis study, carotid arteries, disease onset, fatty plaque, first venture, heart attacks, hormone levels, hormone replacement therapy, line of inquiry, media thickness, objective measures, observational study, patient evaluation, perimenopausal, physiologic changes, plaque accumulation, premenopausal, rapid transition, subjective factors, thickness measurement