Oxygen, MRI combo may help determine cancer therapy success
June 4th, 2009 - 4:19 pm ICT by ANI ( Leave a comment )Washington, June 4 (ANI): Researchers at UT Southwestern Medical Center claim that a simple magnetic resonance imaging (MRI) test that involves breathing oxygen may help doctors determine the best treatment for cancer patients.
Prior research has shown that the amount of oxygen present in a tumor can be a predictor of how well a patient will respond to treatment. Tumors with little oxygen tend to grow stronger and resist both radiotherapy and chemotherapy.
However, until now, the only way to gauge the oxygen level in a tumor, and thus determine which treatment might be more effective, was to insert a huge needle directly into the cancerous tumor.
The new technique, known as BOLD (blood oxygen level dependent) MRI, can detect oxygen levels in tumors without the need for an invasive procedure. The patient need only be able to breathe in oxygen when undergoing an MRI.
“The patient simply inhales pure oxygen, which then circulates through the bloodstream, including to the tumors,” said Dr. Ralph Mason, professor of radiology, director of the UT Southwestern Cancer Imaging Center and senior author of a study appearing online and in a future edition of Magnetic Resonance in Medicine.
“Using MRI, we can then go in and estimate how much oxygen a particular tumor is taking up, providing us some insight into how the tumor is behaving and what sort of treatment might be effective,” the expert added.
The most important finding, Dr. Mason said, is that BOLD MRI performed as well as the standard yet more invasive procedure for viewing tumors. (ANI)
- New technique diagnoses brain cancers non-invasively - Jan 29, 2012
- New treatment shows promise in the fight against breast cancer - Mar 30, 2011
- Protein that thwarts tumor invasion uncovered - Jun 06, 2010
- Study links adrenal gland hormone to brain hypertension - Nov 10, 2010
- Now, remove uterine fibroids the painless way - Jul 06, 2010
- Biomarkers to predict brain tumour's response to therapy identified - Jun 24, 2009
- 3-D mapping breakthrough helps docs remove fist-sized tumour from a woman's brain - Jul 15, 2009
- MRI may predict stroke onset - Nov 03, 2010
- MRI scan 'better' than invasive tests for heart patients - Dec 23, 2011
- New prostate cancer imaging technique can 'see' tumors grow - Dec 03, 2010
- Why hypertensive people's BP increases during exercise - Apr 05, 2011
- New hope for late-stage liver cancer patients - Dec 15, 2010
- Brain scans may help early detection of Alzheimer's - Apr 12, 2011
- Synthetic compound may lead to drugs to fight pancreatic, lung cancer - Mar 10, 2011
- MRI can help locate prostate cancer recurrence at extremely low PSA levels - Apr 30, 2011
Tags: blood oxygen level, bloodstream, breathing oxygen, cancer imaging, cancer patients, cancer therapy, cancerous tumor, chemotherapy, dr mason, imaging center, invasive procedure, magnetic resonance imaging, magnetic resonance imaging mri, magnetic resonance in medicine, mri test, oxygen levels, radiotherapy, ralph mason, resonance imaging mri, southwestern medical center