Oxygen, MRI combo may help determine cancer therapy success
June 4th, 2009 - 4:19 pm ICT by ANI
- Washington, June 4 (ANI): Researchers at UT Southwestern Medical Center claim that a simple magnetic resonance imaging (MRI) test that involves breathing oxygen may help doctors determine the best treatment for cancer patients.
Prior research has shown that the amount of oxygen present in a tumor can be a predictor of how well a patient will respond to treatment. Tumors with little oxygen tend to grow stronger and resist both radiotherapy and chemotherapy.
However, until now, the only way to gauge the oxygen level in a tumor, and thus determine which treatment might be more effective, was to insert a huge needle directly into the cancerous tumor.
The new technique, known as BOLD (blood oxygen level dependent) MRI, can detect oxygen levels in tumors without the need for an invasive procedure. The patient need only be able to breathe in oxygen when undergoing an MRI.
“The patient simply inhales pure oxygen, which then circulates through the bloodstream, including to the tumors,” said Dr. Ralph Mason, professor of radiology, director of the UT Southwestern Cancer Imaging Center and senior author of a study appearing online and in a future edition of Magnetic Resonance in Medicine.
“Using MRI, we can then go in and estimate how much oxygen a particular tumor is taking up, providing us some insight into how the tumor is behaving and what sort of treatment might be effective,” the expert added.
The most important finding, Dr. Mason said, is that BOLD MRI performed as well as the standard yet more invasive procedure for viewing tumors. (ANI)
Sphere: Related ContentRelated Stories
- 3-D mapping breakthrough helps docs remove fist-sized tumour from a woman's brain - Jul 15, 2009
- Biomarkers to predict brain tumour's response to therapy identified - Jun 24, 2009
- New light-emitting biomaterial may revolutionise tumour imaging - Aug 11, 2009
- New implantable device can help monitor cancer for months after biopsy - May 14, 2009
- Now, breast MRI scan to determine need for radiation therapy sans surgery - Sep 22, 2008
- Scientists use fireflies glow gene to track cancer drugs effectiveness - May 31, 2008
- Scientists use titanium dioxide nanoparticles to kill cancer cells, sparing healthy ones - Aug 20, 2009
- Asia Pacific’s most advanced CyberKnife® launched at Apollo Speciality Cancer Hospital - Feb 14, 2009
- World's first breakthrough in using non-invasive brain surgery to treat patients - Jun 23, 2009
- Gene that makes colon cancer resistant to treatment identified - May 19, 2009
- blood oxygen level
- bloodstream
- breathing oxygen
- cancer imaging
- cancer patients
- cancer therapy
- cancerous tumor
- chemotherapy
- dr mason
- imaging center
- invasive procedure
- magnetic resonance imaging
- magnetic resonance imaging mri
- magnetic resonance in medicine
- mri test
- oxygen levels
- radiotherapy
- ralph mason
- resonance imaging mri
- southwestern medical center
Posted in Health Science, |