Obstructive sleep apnea ‘can make diabetes worse’January 15th, 2010 - 1:51 pm ICT by ANI
Washington, Jan 15 (ANI): A new study conducted by researchers at the University of Chicago has shown that obstructive Sleep Apnea (OSA) adversely affects glucose control in patients with type 2 diabetes.
Lead author, Renee S. Aronsohn, instructor of medicine at the University of Chicago, said that study ‘demonstrates for the first time that there is a clear, graded, inverse relationship between OSA severity and glucose control in patients with type 2 diabetes.’
The study also confirmed other reports that undiagnosed OSA is very common among patients with type 2 diabetes, indicating that it is largely unrecognized additional medical risk factor in these patients.
Dr. Aronsohn and colleagues consecutively recruited patients with type 2 diabetes from outpatient clinics to participate in the study.
The participants were interviewed to assess their diabetes history, medical history and medications, and level of physical activity.
Height and weight measurements were also taken, and each participant’s sleep/wake cycles were monitored for five days using wrist actigraphy and self-reported sleep logs.
Finally, participants underwent an overnight polysomnography test for OSA , and glucose control was assessed by obtaining a blood sample for hemoglobin A1c (HbA1c) measurement, the main clinical marker of glycemic control in diabetes
In total, 60 patients were included in the study’s final analysis. More than three-quarters (77 percent) of participants had OSA, but only five had been previously evaluated for the disease, and none were undergoing treatment. Of the study sample, 38 percent (23) were classified as having mild OSA, 25 percent (15) had moderate OSA and the 13 percent (8) had severe OSA.
The researchers found that more severe OSA was associated with poorer glucose control, implying a role more severe diabetes with potentially more complications.
Relative to patients without OSA, the presence of mild, moderate or severe OSA significantly increased mean adjusted HbA1c values by 1.49 percent, 1.93 percent, and 3.69 percent respectively.
These effect sizes are comparable to those of widely used hypoglycemic medications, meaning that having OSA may negate the beneficial effects of
“Our findings have important clinical implications as they support the hypothesis that reducing the severity of OSA may improve glycemic control. Thus effective treatment of OSA may represent a novel and non-pharmacologic intervention in the management of type 2 diabetes,” said Dr. Aronsohn.
The findings have been published online ahead of print publication in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. (ANI)
- Structured exercise training helps lower diabetics' blood sugar - May 04, 2011
- Combining aerobic and resistance training helpful for diabetics - Nov 24, 2010
- Scientists uncover gut bug link to type 2 diabetes - Mar 14, 2012
- Blood glucose levels indicator of retinopathy risk - Feb 15, 2011
- Intense diabetes treatment could make sugar levels go 'too low' - Jan 27, 2010
- Insulin pumps may benefit diabetics - Jan 16, 2010
- 2 tests better than 1 for diagnosing diabetes in overweight children - May 03, 2011
- Severe sleep apnea reduces nightmare recall frequency - Feb 15, 2010
- White rice increases risk of type 2 diabetes - Mar 16, 2012
- Hemoglobin A1c test better indicator of diabetes risk - Mar 04, 2010
- Exenatide - a physiological option for a pathological disease. - Sep 17, 2009
- Sleep apnea occurring during REM sleep linked to type 2 diabetes - Jun 16, 2009
- Obstructive sleep apnea patients at increased heart disease risk - Jan 25, 2010
- Nicotine raises blood sugar among diabetic smokers: Study - Mar 28, 2011
- Diabetes linked to irregular heartbeat - Apr 23, 2010
Tags: actigraphy, aronsohn, blood sample, diabetes history, glucose control, height and weight, hemoglobin a1c, inverse relationship, medical history, medical risk, osa, outpatient clinics, patients with type, risk factor, sleep apnea, three quarters, type 2 diabetes, undergoing treatment, wake cycles, weight measurements