No clear link between lack of vitamin D and depression

March 18th, 2009 - 12:33 pm ICT by ANI  

Washington, Mar 18 (ANI): A new study by researchers at the University of Warwick has shown that there is no clear link between lack of vitamin D and depression.

Lack of Vitamin D has been related to depression and the symptoms of Seasonal Affective Disorder (SAD).

Exposure to sunlight stimulates vitamin D in the skin and a shortage of sunlight in the winter has been put forward as one possible cause of SAD.

However, Warwick Medical School researchers, led by Dr Oscar Franco, have found low levels of vitamin D in the blood may not be associated with depression.

In the study, the researchers recruited more than 3,000 people and tested levels of vitamin D (25-hydroxyvitamin D) in the blood. They then carried out a questionnaire with the participants to assess the prevalence of depressive symptoms.

Vitamin D deficiency exists when the concentration of 25-hydroxy-vitamin D (25-OH-D) in the blood serum occurs at 12ng/ml (nanograms/millilitre) or less. The normal concentration of 25-hydroxy-vitamin D in the blood serum is 25-50ng/ml.

The researchers found there was no clear association between depressive symptoms and the concentration of vitamin D in the blood.

Few studies have explored the association between blood 25-hydroxyvitamin D concentrations and depression in the general population. A deficiency of vitamin D has also been attributed to several chronic diseases, including osteoporosis, common cancers, autoimmune and cardiovascular diseases, Dr Oscar Franco, Assistant Clinical Professor in Public Health, said.

The researchers recruited 3,262 community residents aged 50-70 from Beijing and Shanghai in China.

Franco said his study did not evaluate whether the depressive symptoms were seasonal and suggested more studies needed to be done.

Previous studies into the effects of vitamin D supplementation have produced mixed results. More studies are still needed to evaluate whether vitamin D is associated with seasonal affective disorders, but our study does raise questions about the effects of taking more vitamin D to combat depressive symptoms, Franco said.

This study was carried out in collaboration with colleagues from the Institute for Nutritional Sciences, Chinese Academy of Sciences in China.

The study has been published in the Journal of Affective Disorders. (ANI)

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