New discovery may help fight breast cancerJanuary 4th, 2011 - 2:16 pm ICT by ANI
Washington, Jan 4 (ANI): Scientists have made a new discovery, which may become a new weapon in fight against breast cancer.
For the first time, researchers at Wake Forest University Baptist Medical Center have shown that a peptide found in blood and tissue inhibits the growth of human breast tumors in mice.
Patricia E. Gallagher and E. Ann Tallant demonstrated that the peptide angiotensin-(1-7) attacked breast cancer in two ways: by inhibiting the growth of the breast cancer cells themselves and by inhibiting the growth of cancer-associated fibroblasts (CAFs), cells found in the tumor microenvironment — the tissue surrounding the tumor.
In this study, mice were injected with human breast cancer cells to form the two most common types of breast tumors - estrogen-receptor and HER2 sensitive.
Once the tumors grew, the mice were injected with either angiotensin-(1-7) or saline for 18 days. In the mice treated with angiotensin-(1-7), there was a 40 percent reduction in tumor size as compared to the saline-injected mice.
Breast tumor fibrosis also was reduced by 64 to 75 percent in the mice treated with the peptide as compared to the saline-injected mice.
The finding has been recently published in the journal Cancer Research. (ANI)
- Scientists provide genetic evidence that antioxidants can help treat cancer - Feb 16, 2011
- New way to screen breast cancer cells' ability to metastasize - Jan 09, 2011
- Lactate's role in development of breast cancer - Apr 19, 2010
- New treatment shows promise in the fight against breast cancer - Mar 30, 2011
- World's first anti-obesity shot promising - Jul 09, 2012
- Fat stem cells for breast reconstruction safe when cancer is dormant - Sep 17, 2010
- How breast cancer cells dodge immune system and survive - Feb 02, 2011
- 'Immune profile' may guide chemotherapy for breast cancer - Apr 04, 2011
- Key culprit in breast cancer metastasis identified - Feb 17, 2011
- Mechanism limiting scar formation discovered - Jun 11, 2010
- New 'nanodrug' can attack breast cancer cells from the inside out - Mar 30, 2011
- Researchers discover mechanism that limits scar formation - Jun 12, 2010
- Broccoli may help fight breast cancer - May 04, 2010
- Potential therapeutic target across a range of cancer types found - Oct 21, 2010
- Protein that fuels inflammation in pancreatic and breast tumors identified - Feb 22, 2011
Tags: baptist medical center, breast cancer, breast cancer cells, breast tumor, breast tumors, cancer research, fight breast cancer, forest university baptist medical, human breast cancer, journal cancer, new discovery, new weapon, peptide, saline, time researchers, tumor microenvironment, tumor size, university baptist medical center, wake forest university, wake forest university baptist medical center