Migraine with aura in midlife may lead to brain lesionsJune 24th, 2009 - 12:47 pm ICT by ANI
Washington, June 24 (ANI): Women who experience migraines with aura (sensory disturbances, such as with vision, balance or speech) during midlife are at increased risk of developing brain lesions in later life, says a new study.
The research has been published in the June 24 issue of JAMA.
Around one-third of individuals with migraine experience neurological aura symptoms before headache onset (migraine with aura).
Now, in the latest study, Ann I. Scher, Ph.D., of Uniformed Services University, Bethesda, Md., and colleagues examined the relationship of midlife migraine symptoms and late-life infarct (tissue death)-like lesions evident on MRI.
The study included 4,689 men and women in Reykjavik, Iceland (born between 1907-1935; 57 percent women) who were followed-up since 1967, examined, and interviewed about migraine symptoms in midlife (average age, 51 years; range, 33-65 years).
Between 2002 and 2006, more than 26 years later, brain MRIs were performed. Participants reporting headaches once or more per month were asked about migraine symptoms and were classified as having migraine without aura, migraine with aura, or nonmigraine headache.
A comprehensive cardiovascular risk assessment was performed at examinations. Infarct-like lesions were present on MRI in 39.3 percent of men and 24.6 percent of women.
After adjusting for age, sex, and follow-up time, participants with midlife migraine with aura were at increased risk for total infarct-like lesions. Lesions in the cerebellum, but not in other locations of the brain, were more prevalent in women with migraine with aura compared with women without headache (23 percent vs. 15 percent); there was no difference in prevalence for men (19 percent vs. 21 percent).
The relationship between migraine with aura and cerebellar infarcts was only significant in women, but was not statistically different by the age at which headache symptoms were assessed.
Migraine without aura and nonmigraine headache were not associated with an increased risk of lesions. The clinical significance of the infarct-like lesions, such as whether the individuals with them had any symptoms, was not assessed. (ANI)
- Migraines do not hurt your brain - Aug 12, 2012
- Migraines, headaches 'do not increase risk of cognitive decline' - Jan 20, 2011
- Migraine sufferers 'at higher risk of dying from heart disease' - Aug 25, 2010
- Weight loss surgery can help alleviate migraines - Mar 29, 2011
- Midlife crisis could be linked with dementia - May 08, 2012
- Migraine likely to double risk of heart attacks - Feb 11, 2010
- Migraine headaches in kids linked to common heart defect - Mar 31, 2011
- Pelvic pain may lead to migraine in women - Dec 26, 2010
- 'Silent' brain damage could point to increased stroke risk - Jun 08, 2010
- Study reveals that migraines may lead to depression in women - Feb 23, 2012
- Preventive medication, behavior changes help fights frequent migraines - Oct 12, 2010
- Migraine 'doubles heart attack risk' - Feb 11, 2010
- Genes linked to migraine discovered - Jun 13, 2011
- Ibuprofen may help people suffering from migraine headaches - Oct 06, 2010
- Breast cancer risk 'can be assessed by examining breast milk' - Apr 05, 2011
Tags: age sex, bethesda md, brain lesions, cardiovascular risk, cerebellar, cerebellum, headache symptoms, infarct, infarcts, jama, migraine, migraine symptoms, mris, reykjavik iceland, risk assessment, scher, sensory disturbances, time participants, tissue death, uniformed services university