Measles virus may offer prostate cancer treatmentJanuary 22nd, 2009 - 2:41 pm ICT by ANI
Washington, Jan 22 (ANI): A new study has found that certain measles vaccine strain derivatives may offer effective treatment for prostate cancer patients.
Certain strains including the one known as MV-CEA is found to effectively infect, replicate in and kill prostate cancer cells.
With help of virotherapy, the researchers found, that the median survival time of MV-CEA-treated mice almost doubled, and complete tumour regression was observed in one-fifth of treated animals.
Based on our preclinical results as well as the safety of measles derivatives in clinical trials against other tumour types, these viral strains could represent excellent candidates for clinical testing against advanced prostate cancer, including androgen resistant tumours, said Evanthia Galanis, M.D., of the Mayo Clinic, senior author of the study.
These strains of measles virus are used as therapeutic agents against cancer that demonstrates no cross-resistance with existing treatment approaches, and can therefore be combined with conventional treatment methods.
The virotherapy agent can easily be applied directly to the prostate tumour via ultrasound-guided needle injections and close monitoring of therapy can be achieved by non-invasive techniques including ultrasound and MRI.
This study is published in The Prostate. (ANI)
- Measles virus derivatives boon for prostate cancer - Jan 22, 2009
- Drug for rare childhood cancer may help prevent prostate cancer spread - Apr 30, 2011
- Potent anticancer drug isolated from weed - Jul 10, 2012
- Gene fusion is the 'smoking gun' in the development of prostate cancer: Study - May 19, 2010
- Hormone therapy 'doubles survival chances in men with prostate cancer' - Mar 25, 2011
- Beehive extract may arrest prostate cancer - May 06, 2012
- Researchers look at new treatment for prostate cancer - Nov 15, 2010
- Prostate cancer treatment 'ups risk of colorectal cancer' - Nov 16, 2010
- New ultrasound technology can accurately spot prostate cancer tumours - Dec 09, 2010
- Scientists find new way to 'starve' cancer cells - Apr 05, 2011
- Australian scientists identify new way to treat prostate cancer - Feb 26, 2010
- Surgery effective for aggressive prostate cancer patients - Sep 28, 2010
- Male sex hormones that mutate in prostate cancer identified - Nov 15, 2010
- Combo therapy may overcome Herceptin-resistant breast cancer - Mar 14, 2011
- New treatment shows promise in the fight against breast cancer - Mar 30, 2011
Tags: cea, conventional treatment, cross resistance, invasive techniques, mayo clinic, measles vaccine, median survival, one fifth, preclinical results, prostate cancer, prostate cancer cells, prostate cancer patients, prostate cancer treatment, prostate tumour, survival time, therapeutic agents, treatment approaches, tumour types, vaccine strain, viral strains