Immunosuppressant may be remedy for dry-eye syndrome

February 11th, 2009 - 12:29 pm ICT by IANS  

“Patients with dry-eye syndrome have more difficulty reading, carrying out professional work, using a computer, watching television and driving compared with those without dry eyes,” the study authors wrote. It affects 15 to 34 percent of older people.

Using data from two randomised clinical trials and Food and Drug Administration (FDA) files, Melissa M. Brown, University of Pennsylvania School of Medicine (UPSM), Philadelphia, and colleagues assessed the comparative effectiveness and cost-effectiveness of eye drops.

These eye-drops contained a 0.05 percent emulsion of the drug cyclosporine for patients whose moderate to severe dry eye syndrome did not respond to conventional therapy.

When compared with eye drops containing only lubricant, the cyclosporine drops were associated with a 4.3 percent improvement in quality of life, and conferred a 7.1 percent improvement over no treatment, said an UPSM release.

These findings were reported in the February issue of Archives of Ophthalmology, a JAMA publication.

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