Genetically engineered mosquitoes thwart dengue spreadersNovember 12th, 2010 - 3:07 pm ICT by ANI
London, Nov 12 (ANI): Fight against dengue would soon become more efficient, as scientists have successfully conducted an outdoor trial of genetically modified mosquitoes to sabotage the dengue spreaders.
By the end of the six-month trial, populations of Aedes aegypti mosquitoes, which spread the dengue virus, had plummeted, reports New Scientist.
“It’s a proof of principle, that it works,” said Angela Harris of the Mosquito Control and Research Unit on the Caribbean island of Grand Cayman, where the trial took place.
The MCRU conducted the trial with Oxitec, the company in Oxford that bred the GM mosquitoes.
Oxitec breeds millions of males carrying an altered gene called tTA, which they pass down when they mate with females.
The lethal gene overcomes the gene-reading machinery of larva and pupae, preventing them from growing properly and causing them to die before adulthood, breaking the insects’ life cycle.
The researchers measured depletion of the population through weekly checks on eggs laid by the females in jam-jar-sized pots that were randomly dispersed throughout the trial plot.
For the first three months or so, the proportion of pots containing at least one egg gradually rose, reaching a peak of more than 60 per cent But by the end of the experiment the proportion had fallen to 10 per cent.
The researchers concluded that the number of females laying eggs nosedived because most were dying as larvae. The resources consumed by the doomed larvae and pupae before they die vie with normal rivals for resources, which helped to reduce the population. (ANI)
- Can GM mosquitoes wipe out dengue? - Oct 24, 2010
- Malaysia release of GM insects 'may create uncontrollable new species' - Jan 27, 2011
- 'Travel, urbanisation have led to 50-fold rise in dengue cases' - Sep 17, 2012
- Scientists create flightless mosquitoes to control dengue fever - Feb 23, 2010
- New discovery could shrink dengue-spreading mosquito population - Dec 03, 2010
- Chemistry of mosquito sex could be key to controlling dengue fever - Mar 20, 2011
- Making mosquitoes pay for every bite - Jul 20, 2011
- Brazil to breed mosquitoes to fight dengue - Jul 09, 2012
- GM mosquito trials raise concern in India - Jul 23, 2009
- Coming soon: A trap to trick pregnant mosquitoes! - Dec 26, 2010
- Lahore dengue toll rises to 127 - Oct 02, 2011
- GM mosquitoes released to fight dengue in Cayman Isles - Nov 14, 2010
- Now a portable tool to detect dengue mosquitoes! - May 23, 2012
- Male mosquitoes' proteins may affect females' behaviour, physiology - Mar 16, 2011
- Lahore dengue toll rises to 36 - Sep 18, 2011
Tags: adulthood, angela harris, caribbean island, dengue virus, first three months, gm mosquitoes, grand cayman, insects life cycle, jam jar, larva, larvae, lethal gene, mosquito, mosquito control, mosquitoes, new scientist, pots, pupae, rivals, trial plot