Genetic risk for anxiety, depression not predestined: StudyApril 30th, 2009 - 2:27 pm ICT by ANI
Washington, April 30 (ANI): Previous studies have provided a strong basis of support for hypothesis that individuals with particular genotypes are predestined to negative life outcomes such as depression, anxiety disorders. But now, a new study has challenged this view.
Researchers studied infant monkeys from four different rearing conditions to examine how social context and different forms of early adversity interact with genotype to influence behaviour.
Animals reared in small social groups were more likely to be aggressive and anxious, particularly among those with a low activity MAOA genotype.
However, no genotype effects were evident in monkeys reared in larger social cages.
There are some circumstances in a child’s development - such as abusive parenting - that everyone would agree constitutes “adversity.”
However, this study suggests that other, subtler features of the broader social environment influence development, and that genes that affect our behavioral responses are sensitive to these influences.
So even though an infant may be reared with its nurturing mother, the relative absence of other social partners, for both the mother and the infant, can result in the infant developing an anxious style of responding to challenges, particularly if it possesses a “risky” genotype.
Of particular significance, said senior author John Capitanio, Ph.D., is “that animals that were raised in rich, complex settings with mothers, other kin, and peers, were completely protected from the potentially deleterious effects of having the ‘risky’ form of the MAOA gene.”
The study is published in the May 1st issue of Biological Psychiatry. (ANI)
- Certain genetic makeup reduces the brain's neurons in drug addicts - Mar 08, 2011
- 'Midas touch' gene that makes people brilliant businessmen discovered - Dec 29, 2010
- Good luck at gambling 'may be in your genes' - Dec 08, 2010
- Social ranking can influence genetic functions - Apr 10, 2012
- ADHD medication may delay boys' puberty - Sep 21, 2011
- Criminal behaviour could be 'all in the genes' - Nov 26, 2010
- Abusive mothering leads to increased stress among kids - Jun 22, 2010
- Depressed mums less responsive to babies' cries: Study - Feb 23, 2011
- Exposure to worm infection in the womb 'cuts eczema risk' - Jan 29, 2011
- Breastfeeding key to keeping infant gut healthy - Apr 30, 2012
- Heavier monkey moms produce better milk - Mar 06, 2010
- It's natural for girls to play with dolls and boys to like guns - Dec 21, 2010
- First genetic test for predicting IVF success developed - Jan 16, 2011
- Why statins work for some people, but not for all - Apr 22, 2010
- Monkeys go bananas at the sight of flying squirrel - Jul 31, 2010
Tags: adversity, anxiety disorders, author john, behavioral responses, biological psychiatry, capitanio, deleterious effects, depression anxiety, genetic risk, genotype, genotypes, infant monkeys, influence development, life outcomes, maoa, relative absence, social context, social environment, social groups, social partners