Further evidence on benefits of BP drugs in diabetic retinopathy treatmentFebruary 25th, 2010 - 5:40 pm ICT by ANI
Washington, Feb 25 (ANI): A new study has offered more evidence that certain high blood pressure drugs may be useful in preventing and treating diabetic retinopathy, the leading cause of vision loss in people with diabetes.
Scientists in Massachusetts say their study could lead to new ways to prevent or treat the sight-threatening disease.
Edward Feener and his colleagues point out that diabetic retinopathy is a common complication of diabetes, which affects millions of people worldwide.
It involves damage to blood vessels in the retina, the light sensitive tissue in the back of the eye.
Previous studies suggested that drugs used to treat high blood pressure, including ACE inhibitors and angiotensin receptor blockers (ARBs), may help prevent the condition.
The scientists analyzed proteins from the retinas laboratory mice with normal blood pressure and diabetes and compared them to those of non-diabetic mice.
They identified 65 abnormal proteins in the diabetic mice out of more than 1,700 proteins in the study.
Treatment with the ARB medication, candesartan, prevented the abnormal changes in more than 70 percent of the proteins.
The findings are in ACS’ Journal of Proteome Research, a monthly publication. (ANI)
- BP drug not tied to death risk among heart patients - Apr 11, 2012
- BP drug could harm stroke patients - Feb 13, 2011
- Combination ACE inhibitor therapy raises risk of kidney failure, death - Mar 22, 2011
- Anti-hypertensive drug improves multiple sclerosis-related brain inflammation - Jul 29, 2010
- Why hypertensive people's BP increases during exercise - Apr 05, 2011
- Novel approach offers new insights into causes of pre-eclampsia - Oct 07, 2010
- Decrease in protein levels could be sign child will develop diabetes - Apr 26, 2011
- Study links Blood pressure drugs to cancer - Jun 15, 2010
- Potential therapeutic target for diabetic retinopathy identified - Jan 15, 2010
- Blood pressure medications show higher cancer risk: Study - Jun 14, 2010
- How omega-3 fatty acids keep blindness at bay - Feb 10, 2011
- BP drug lowers weight in spite of high fat diet - Apr 13, 2012
- Blood Pressure Drugs Increase Cancer Risk, Study Reveals - Jun 15, 2010
- Two therapies that may slow diabetic eye disease progression found - Jul 24, 2010
- Patients receiving dialysis 'at higher risk for sudden cardiac death' - Nov 15, 2010
Tags: abnormal changes, abnormal proteins, ace inhibitors, acs, acs journal, arb, arbs, blood pressure drugs, blood vessels, candesartan, complication of diabetes, diabetic mice, diabetic retinopathy, high blood pressure, journal of proteome research, laboratory mice, normal blood pressure, receptor blockers, retina, vision loss